Stocks were mixed in intraday trading on Thursday as optimism over a possible coronavirus vaccine was overshadowed by worries that tighter restrictions to control the spread of the virus will lead to further economic damage.
This came after stocks ended lower Wednesday as the gains that came from Pfizer's more promising vaccine data were erased after New York City moved to close public schools again as virus transmission in the nation's largest school system spiked.
In the U.S., deaths have surpassed 250,000, which is the most in the world in a single country, according to Johns Hopkins University.
Experts have predicted the country could soon be reporting 2,000 deaths a day or more, matching or exceeding the spring peak, and that 100,000 to 200,000 more Americans could die in the coming months, The New York Times said in a report.
There are 56 million cases of the coronavirus worldwide, with over 1.3 million deaths. There are 11.5 million cases in the U.S.