Hurricane Maria was downgraded overnight to a strong category 4 as it lashes at the Caribbean. Puerto Rico is bracing for a direct hit today. The National Hurricane Center says some parts of Puerto Rico may be uninhabitable for weeks. Meanwhile, the death toll continues to climb after a powerful earthquake hit Mexico. More than 200 people are dead. The earthquake was a magnitude 7.1 and scores of buildings were destroyed. The Mexican stock exchange is closed and the Mexico City airport is shut down. FedEx (FDX - Get Report) says its profits fell 17% and it's blaming the cyberattack. A hack at its TNT Express in June caused shipping delays in Europe. The shipping giant also said that Hurricane Harvey affected its fiscal 1st quarter results. The Federal Reserve is in focus as it wraps up a 2-day meeting and announced a decision on interest rates.