Yes, former Apple (AAPL) CEO John Sculley is keeping active.

Actually, he is somewhat of a serial entrepreneur.

He is an investor and chief marketing officer at upstart pharmacy benefit manager RxAdvane, which does battle with heavyweights Express Scripts (ESRX) and CVS Health (CVS) . "I think RXAdvance is the most interesting company I have worked at since Apple -- we are disrupting the most vulnerable and expensive area of the market." Sculley said he expects RxAdvance to boast $2 billion in contracted revenue by 2018 and $10 billion by 2020.

Sculley is playing in the healthcare space at a pivotal time.

Amazon has reportedly gained approval to become a wholesale drug distributor in 12 states, according to the St. Louis Post-Dispatch. Apple has been rumored to have shown interest in buying a health clinic provider. Health insurer Aetna (AET) is rumored to be on the the verge of selling out to CVS Health

It won't be super easy for Apple (AAPL)  or Amazon (AMZN) to make big pushes into the healthcare space.

"It would make sense for Amazon to get into healthcare [PBM] industry," Sculley said. "The challenge for Amazon is not that they don't have the technology prowess, it's the complexity of the domain of healthcare." Sculley explained that it would be logical for Amazon to get into the supply chain management side of the business -- the only question being does it partner with someone or build out a drug supply chain of its own.

Apple is a holding in Jim Cramer's Action Alerts PLUS Charitable Trust Portfolio. Want to be alerted before Cramer buys or sells AAPL? Learn more now.

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