Intra-Cellular Leaps; Schizophrenia Drug Shows Less Side Effects-Biotech Movers

Shares of Intra-Cellular Therapies Inc. (ITCI) have popped more than 20%, or $3.82, to $22.79 in premarket trading Thursday, Sept. 7 after the company reported positive topline data in an early study of schizophrenia patients who were switched from standard-of-care antipsychotic medications to the company's lumateperone. Intra- Cellular hopes to market the drug as one with fewer side effects than currently available antipsychotic treatments, which frequently cause motor side effects and/or weight gain, cardiovascular complications, dyslipidemia, and hyperglycemia.Intra-Cellular said the study showed patients switched to statistically significant improvements in body weight, cardiometabolic and endocrine parameters in patients when switched to lumateperone. The systems reverted when patients switched back to previous medications.

Alnylam Pharmaceuticals Inc. (ALNY) has suspended patient trials of its hemophilia drug fitusiran after a patient died while undergoing treatment. Shares of the company were down more than 10% premarket Thursday, dropping $9.02 to $77.00. The company said dosing will be halted in all ongoing fitusiran studies pending further review and development of a risk mitigation strategy. Nevertheless, the company said based on overall consideration of fitusiran's benefit-risk profile, Alnylam "aims to resume dosing as soon as possible upon agreement with global regulatory authorities and with appropriate protocol amendments in place for enhanced patient safety monitoring."

Shares of Neuralstem Inc. (CUR) were up 6.14%, or 7 cents, to $1.21 after the company was awarded two patents protecting its approach for using neural stem cells to treat neurodegenerative disorders.

More from Stocks

Never Buy Stocks Based on Unusual Call Activity: Doug Kass Insider

Never Buy Stocks Based on Unusual Call Activity: Doug Kass Insider

Will Tesla Stock Tumble 33% to $195?

Will Tesla Stock Tumble 33% to $195?

Is Best Buy Sleeping With the Enemy With Amazon Partnership?

Is Best Buy Sleeping With the Enemy With Amazon Partnership?

Video: The S&P 500 Is Failing to Make New Highs

Video: The S&P 500 Is Failing to Make New Highs

Dow, S&P 500 and Nasdaq Finish Lower as Apple, P&G Slump

Dow, S&P 500 and Nasdaq Finish Lower as Apple, P&G Slump