Don't expect to find a t-shirt for sale inside of an Amazon (AMZN - Get Report) owned Whole Foods store.

Following a green light on Thursday, Aug. 24, from the Federal Trade Commission on Amazon's $13.7 billion deal to buy Whole Foods, and the shareholders' yes on Wednesday, Aug. 25, the upscale grocer is set for big changes.

Barclays analyst Karen Short wrote in a note on Friday that Amazon could apply its bookstore prototypes strategy to redoing the traditional grocery story, evident in Whole Foods stores. That means, she wrote, that it will be "clearly showing titles," but "not a bountiful selection" with the "goal of a higher hit selection."

But, Short also pointed out how Whole Foods' stores might no longer try to sell all things, to all people. After all, Amazon wants to run extra profitable Whole Foods stores so that it earns a high return on investment. 

For example:

"A comprehensive analysis of productivity in each department will likely show clear evidence that apparel should be abolished entirely in every store. Vitamins and minerals, while high margin, will also likely be eliminated or drastically paired down from all stores given WFM's drastically higher price positioning in these categories. In the key SKUs [items] that remain, we expect to see drastic price reductions."

More of What's Trending on TheStreet: