The market is still hot. 

So, let's take a look at six stocks that are showing up on unusual volume scans.

Advanced Micro Devices Inc.

  • Wednesday's Volume: 188.29 million
  • Three-Month Average Volume: 68.42 million
  • Volume % Change: 167%

From a technical perspective, Advanced Micro Devices Inc. (AMD - Get Report) exploded higher and broke out above a key downtrend line that dated back to February with monster upside volume flows. Market players should look for a continuation move higher in the short-term if this stock manages to clear some key resistance levels with solid volume.

Traders should look for long-biased trades in AMD as long as it's trending above $13.40 or $12.77 and then once it clears or closes above Wednesday's intraday high of $14.01 with volume that hits near or above 68.42 million shares. Some possible upside targets off that move are $14.75 to its 52-week high of $15.55, or even $17 to $18 a share.

AveXis Inc.

  • Wednesday's Volume: 2.30 million
  • Three-Month Average Volume: 442,039
  • Volume % Change: 401%

From a technical perspective, AveXis Inc. (AVXS) ripped higher back above both its 20-day at $73.25 and its 50-day at $74.57 with strong upside volume. This high-volume move to the upside is quickly pushing this stock within range of triggering a major breakout trade above a key downtrend line.

Traders should look for long-biased trades in AVXS as long as it's trending above $70 and then once it breaks out above Wednesday's intraday high of $77.50 to $81.69 with volume that hits near or above 442,039 shares. Some possible upside targets off that breakout are $83 to its 52-week high of $85.98, or even $90 a share.

Twitter Inc.

  • Wednesday's Volume: 23.73 million
  • Three-Month Average Volume: 17.71 million
  • Volume % Change: 65%

From a technical perspective, Twitter Inc. (TWTR - Get Report) spiked higher back above both its 200-day at $17.46 and its 20-day at $17.58 with above-average volume flows. Market players should look for a continuation move to the upside in the short-term if this stock manages to take out its next key resistance levels with solid volume.

Traders should look for long-biased trades in TWTR as long as it's trending above its 50-day at $17.19 or above $16.50 and then once it clears Wednesday's intraday high of $18.04 to more resistance at $18.72 with volume that hits near or above 17.71 million shares. If that move gets underway soon, then this stock will set up to re-test its next major resistance levels at $19.78 to $21 a share.

Prothena Corporation plc

  • Wednesday's Volume: 384,000
  • Three-Month Average Volume: 255,610
  • Volume % Change: 65%

From a technical perspective, Prothena Corporation plc (PRTA - Get Report) ripped sharply higher right off its 50-day at $53.19 and back above its 200-day at $54.05 with above-average volume. This high-volume jump to the upside is now quickly bringing this stock within range of triggering a major breakout trade above a key downtrend line that dates back from March.

Traders should look for long-biased trades in PRTA as long as it's trending above key support around $52 and then once it breaks out above a downtrend line that will trigger over Wednesday's intraday high of $56.64 and above more resistance at $58.45 with volume that hits near or above 255,610 shares. Some possible upside targets off that breakout are its next key resistance levels at $63.14 to its 52-week high of $68.18 a share.

Viacom Inc.

  • Wednesday's Volume: 376,000
  • Three-Month Average Volume: 88,362
  • Volume % Change: 271%

From a technical perspective, Viacom Inc. (VIA - Get Report) spiked notably higher right off its 20-day at $38.82 with heavy upside volume. This stock has been uptrending over the past two months, with shares moving higher off its recent low of $36.07 to its recent high of $40.50 a share. During that move, this stock has been making mostly higher lows and higher highs, which is bullish technical price action.

Traders should look for long-biased trades in VIA as long as it's trending above some near-term support levels at $38.12 or $37.71 and then once it breaks out above its 50-day at $40.39 to $40.50 with volume that hits near or above 88,362 shares. Some possible upside targets off that breakout are its 200-day at $41.96 to $44.50, or even $46 to $47 a share.

JD.com Inc.

  • Wednesday's Volume: 15.99 million
  • Three-Month Average Volume: 9.80 million
  • Volume % Change: 110%

From a technical perspective, JD.com Inc. (JD - Get Report) spiked higher back above its 20-day at $39.97 and into breakout territory above $40.32 with heavy upside volume. This high-volume rip is quickly pushing this stock within range of triggering another big breakout trade.

Traders should look for long-biased trades in JD as long as it's trending above its 50-day at $37.96 and then once it breaks out above Wednesday's intraday high of $41.27 to its all-time high of $43.80 with volume that hits near or above 9.80 million shares. Some possible upside targets off that breakout are $50 to $55 a share.

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This article is commentary by an independent contributor. At the time of publication, the author held no positions in the stocks mentioned.