Shares of Aerie Pharmaceuticals (AERI - Get Report) jumped 37.4% to $55.65 in premarket trading on Thursday. The Irvine, Calif.-based firm after the market close on Wedneday unveiled positive topline efficacy results in a phase three study of Roclatan, an eye drop combining Rhopressa (netarsudil ophthalmic solution) with prostaglandin analogue (PGA) latanoprost.

Puma Biotechnology (PBYI - Get Report) shares continue rising after the company's breast cancer treatment neratinib received a recommendation late Wednesday for FDA approval from the agency's Oncologic Drugs Advisory Committee. Thursday the shares were up 1.27% to $75.90 in pre-market trading. The shares are up dramatically since Friday, when they closed at $37.80.

Meanwhile, shares of BioCryst Pharmaceuticals (BCRX - Get Report) rose 19.1% to $6.11. The Research Triangle Park, N.C.-based firm on Thursday announced additional positive results from a second interim analysis of a phase two study of BCX7353 as a preventative treatment to reduce the frequency of attacks in patients with hereditary angioedema.

Other biotech movers include GW Pharmaceuticals (GWPH) , whose American depository receipts were up 4.4% to $111. The London firm, together with its U.S. subsidiary Greenwich Biosciences, said Wednesday that The New England Journal of Medicine has published results from a phase three study of Epidiolex (cannabidiol) in children with Dravet syndrome.

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