Updated to include Walgreens earnings.
 
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Here are five things you must know for Wednesday, April 5:

1. -- U.S. stock futures were mixed Wednesday as investors awaited the release of the minutes from the Federal Reserve meeting in March, and a snapshot on the U.S. labor market.

European stocks also were trading mixed while Asian shares finished Wednesday's session with gains.

Stocks in the U.S. on Tuesday rose following an unsettled session with gains in Caterpillar  (CAT - Get Report) offsetting pressure from the consumer sector.

The Dow Jones Industrial Average rose 0.19%, the S&P 500 gained 0.05% and the  Nasdaq finished up 0.07%.
 
Wall Street remained nervous Wednesday ahead of the meeting between Donald Trump and China's President Xi Jinping on Thursday and Friday. Trump and Xi, set to meet at Mar-a-Lago in Florida, are expected to discuss North Korea, trade, and currencies. Trump has been highly critical of China, accusing the country of manipulating its currency and stealing U.S. jobs.
 
The ADP National Employment Report for March will be released at 8:15 a.m. EDT, while minutes from the March 15 meeting of the Fed will be issued at 2 p.m. At the meeting, the central bank raised interest rates for the second time in three months.

The economic calendar in the U.S. on Wednesday also includes the ISM Non-Manufacturing Index for March at 10 a.m., and Oil Inventories for the week ended March 31, at 10:30 a.m.

Walgreens (WBA - Get Report) reported fiscal second-quarter adjusted earnings of $1.36 a share, 1 cent below estimates. Revenue in the period was $29.45 billion; analysts expected $30.26 billion.

The stock fell 1% in premarket trading on Wednesday.

Walgreens is a holding in Jim Cramer's Action Alerts PLUS Charitable Trust Portfolio. Want to be alerted before Cramer buys or sells WBA? Learn more now.

Earnings are also expected Wednesday from Bed, Bath & Beyond  (BBBY - Get Report) , Monsanto (MON  and Yum! China  (YUMC - Get Report) .

2. -- Shares of Panera Bread (PNRA were rising 13% in premarket trading on Wednesday to $310 after the salad and sandwich chain agreed to be bought by JAB Holdings for about $7.5 billion.

Panera said Wednesday it will be acquired by JAB Holdings for $315 a share in cash. The purchase prices represents a 30% premium to Panera's 30-day average stock price as of March 31, the last trading day before speculation arose about a potential transaction.

"Our success for shareholders is the byproduct of our commitment to long-term decision making and operating in the interest of all stakeholders, including guests, associates, and franchisees," Panera Bread founder Ron Shaich said in a statement. "We believe this transaction with JAB offers the best way to continue to operate with this approach. We are pleased to join with JAB, a private investor with an equally long-term perspective, as well as a deep commitment to our strategic plan."

Panera Bread is a logical fit for JAB Holdings, the growing food conglomerate that owns Krispy Kreme, Keurig and Peet's Coffee, among other assets. Joining forces with JAB will bring the Panera Brand overseas and leverage its top-flight digital ordering capabilities across many other channels.

3. -- Amazon (AMZN - Get Report)  struck a $50 million deal to stream part of the NFL's Thursday Night Football package.

The 10 games broadcast by NBC and CBS next season will be available to Amazon Prime subscribers.

The deal is for one year, according to published reports, and Amazon beat out Twitter -- which paid $10 million for 10 games last season -- Facebook and Alphabet's YouTube for the rights.

Separately, Amazon reached an agreement with the Federal Trade Commission to end litigation that was holding up the reimbursement of more than $70 million in unauthorized in-app purchases made by children.

The FTC sued Amazon in 2014, accusing it of allowing children to make purchases without their guardians' permission while using apps on tablets such as the Kindle Fire.

 
4. -- The U.S. marketing chief for McDonald's ( MCD - Get Report) , Deborah Wahl, will be leaving the company after three years with the fast-food giant.
 
The management shake-up at McDonald's also included Lance Richards, vice president of menu strategy, and Julia Vander Ploeg, the company's vice president of digital.
 
Morgan Flatley, the former chief marketing officer of Global Nutrition at PepsiCo, will replace Wahl.
 
McDonald's has been working to improve its food quality and has expanded its popular all-day breakfast menu, but has been losing traffic to competitors like Chipotle.
 
One executive conceded last month that she believes McDonald's has lost "hundreds of millions of customers." 
 
5. --  Payless ShoeSource is the latest retailer to file for bankruptcy amid the pressures facing the industry from heightened e-commerce competition, rising rent costs and declining foot traffic. 

The Kansas-based discount shoe store operator said it plans to immediately close nearly 400 underperforming locations in the U.S. and Puerto Rico and "work to aggressively manage the remaining real estate lease portfolio either by modifying terms, or evaluating closures of additional locations." 

"This is a difficult, but necessary, decision driven by the continued challenges of the retail environment which will only intensify," Payless CEO Paul Jones said in a statement.

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