Short-sellers hate being caught short a stock that reports a blowout quarter. When this happens, we often see a tradable short squeeze develop as the bears rush to cover their positions. Even the best short-sellers know, it's never a great idea to stay short once a bullish earnings report sparks a big short-covering rally.

This is why I scan the market for heavily shorted stocks that are about to report earnings. You only need to find a few of these stocks every week to help enhance your portfolio returns.

With that in mind, let's take a look at several stocks that could experience big short squeezes when they rerport earnings this week.

INSYS Therapeutics

My first earnings short-squeeze play is specialty pharmaceutical player INSYS Therapeutics (INSY) , which is set to release numbers Thursday before the market open. Wall Street analysts, on average, expect INSYS Therapeutics to report revenue of $51.15 million on earnings of 2 cents per share.

The current short interest as a percentage of the float for INSYS Therapeutics is extremely high at 63.4%. That means that out of the 18.47 million shares in the tradable float, 11.72 million shares are sold short by the bears.

I would wait until after INSYS Therapeutics reports, and then look for long-biased trades if this stock manages to break out above its 20-day moving average of $11.57 and then above more resistance around $12 with volume that hits near or above 1.08 million shares. If that breakout triggers post-earnings, this stock will set up to re-test or possibly take out its next major overhead resistance levels at its 200-day moving average of $12.75 to $13.30, or even $13.70 to $14 a share.

AveXis

Another potential earnings short-squeeze trading opportunity is clinical-stage gene therapy player AveXis (AVXS) , which is set to release numbers on Thursday after the market close. Wall Street analysts, on average, expect AveXis to report a loss of 80 cents per share.

The current short interest as a percentage of the float for AveXis is extremely high at 35.1%. That means that out of the 15.96 million shares in the tradable float, 5.60 million shares are sold short by the bears.

I would wait until after AveXis reports, and then look for long-biased trades if this stock manages to break out above some key resistance levels at $72.50 to its all-time high of $72.72 with volume that hits near or above 467,932 shares. If that breakout materializes post-earnings, this stock will set up to enter new all-time-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $80 to $85, or even $90 a share.

Athene

Another potential earnings short-squeeze candidate is retirement services player Athene (ATH - Get Report) , which is set to release numbers on Wednesday after the market close. Wall Street analysts, on average, expect Athene to report revenue of $793.58 million on earnings of $1.17 per share.

The current short interest as a percentage of the float for Athene is notable at 6.2%. That means that out of the 59.20 million shares in the tradable float, 3.71 million shares are sold short by the bears.

I would wait until after Athene reports, and then look for long-biased trades if this stock manages to break out above its 20-day moving average of $51.58 to $52 and then above its all-time high of $53.98 with volume that hits near or above 527,265 shares. If that breakout kicks off post-earnings, this stock will set up to enter new all-time-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $60 to $65, or even $70 a share.

Tiffany & Co.

Another earnings short-squeeze prospect is jewelry stores play, Tiffany & Co. (TIF - Get Report) , which is set to release numbers on Friday before the market open. Wall Street analysts, on average, expect Tiffany & Co. to report revenue of $1.22 billion on earnings of $1.39 per share.

The current short interest as a percentage of the float for Tiffany & Co. stands at 9.1%. That means that out of 123.43 million shares in the tradable float, 11.23 million shares are sold short by the bear.

I would wait until after Tiffany & Co. reports, and then look for long-biased trades if this stock manages to break out above some near-term resistance levels at $90 to its 52-week high of $92.74 and then above some past resistance at $93.11 with volume that hits near or above 1.90 million shares. If that breakout fires off post-earnings, then this stock will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $100 to $105 a share.

Omeros

My final earnings short-squeeze trade idea is biopharmaceutical player Omeros (OMER - Get Report) , which is set to release numbers on Thursday after the market close. Wall Street analysts, on average, expect Omeros to report revenue of $12.48 million on a loss of 56 cents per share.

The current short interest as a percentage of the float for Omeros is extremely high at 22%. That means that out of the 40.18 million shares in the tradable float, 8.87 million shares are sold short by the bears.

I would wait until after Omeros reports, and then look for long-biased trades if this stock manages to break out above its 20-day moving average of $11.60 to some more near-term resistance at $12 with volume that hits near or above 377,935 shares. If that breakout hits post-earnings, this stock will set up to re-test or possibly take out its next major overhead resistance levels at $12.40 to $13, or even $13.50 to $14.15 a share.

This article is commentary by an independent contributor. At the time of publication, the author held no positions in the stocks mentioned.