Marc C. Chamberlain, M.D.Dr. Chamberlain was most recently Professor of Neurology and Neurological Surgery at the University of Washington, Fred Hutchinson Cancer Research Center and Seattle Cancer Care Alliance in Seattle, Washington. Dr. Chamberlain has developed many of the methods used today in evaluating and managing neoplastic meningitis. Dr. Chamberlain has focused increasingly on clinical trials for primary brain tumors, hoping to achieve new and better therapies. He has published his work in more than 350 scientific papers in peer-reviewed publications. Dr. Chamberlain received his medical degree in from Columbia University, College of Physicians and Surgeons in New York.About Cascadian Therapeutics Cascadian Therapeutics is a clinical-stage biopharmaceutical company dedicated to developing innovative product candidates for the treatment of cancer. The lead product candidate, tucatinib, also known as ONT-380, is an oral, selective small molecule HER2 inhibitor. Preliminary results from two ongoing Phase 1b studies of tucatinib in combination showed promising systemic activity, a favorable safety profile and encouraging activity against brain metastases. Cascadian Therapeutics is conducting a randomized, double-blind, placebo-controlled Phase 2 study called HER2CLIMB. The study is evaluating tucatinib versus placebo in combination with capecitabine and trastuzumab in late stage HER2+ breast cancer patients, with and without brain metastases, who have previously been treated with a taxane, trastuzumab, pertuzumab and T-DM1. Additional details can be found at www.clinicaltrials.gov (Identifier: NCT02614794) or www.HER2CLIMB.com. For more information and to sign up for email alerts or RSS feeds, please visit www.cascadianrx.com.
Contacts:Monique GreerCascadian Therapeutics206firstname.lastname@example.orgMedia Contact:Brad MilesBMC Communications917email@example.com