THE WOODLANDS, Texas, Nov. 21, 2016 /PRNewswire/ -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX), today announced the appointments of Alexander Santini as chief commercial officer, Kiernan Seth, Ph.D. as vice president of marketing, and Gary Branch as vice president of sales. Mr. Santini will have responsibility for all commercial activities in the United States for telotristat ethyl, an investigational oral drug for the treatment of carcinoid syndrome, with Dr. Seth and Mr. Branch reporting directly to him. "We are pleased to have the core members of the commercial leadership team in place leading into the potential commercialization of telotristat ethyl," said Lexicon president and chief executive officer, Lonnel Coats. "Each member of this unique team brings a tremendous level of expertise that will be crucial in ensuring that telotristat ethyl, if approved, is immediately accessible for patients suffering from carcinoid syndrome." With over 30 years of varied health care experience, Mr. Santini has demonstrated the ability to build, lead and motivate cross functional teams responsible for driving successful product launches and customer service improvements, while building strategic partnerships with key decision makers. Mr. Santini joined Lexicon in April 2015 and was previously responsible for developing the market access and channel management strategy for telotristat ethyl. Prior to joining Lexicon, Mr. Santini served as executive member and vice president of market access for the Bayer U.S. Pharmaceutical organization where he had executive responsibility for market access, pricing, trade and channel management, and payer account management for the entire Bayer U.S. drug portfolio. Prior to Bayer Pharmaceuticals, Mr. Santini held executive leadership roles of increasing responsibility at Berlex Laboratories. Prior to embarking on his career in the pharmaceutical industry, Mr. Santini served as a non-commissioned officer in the U.S. Air Force, where he completed the Radiologic Technology Program at the U.S. Air Force School of Health Care Science and an AAS degree in Business Marketing from Westchester Community College in Valhalla, New York. During his tour of duty Alex was awarded the Certificate of Appreciation from the U.S. Secretary of Defense for exemplary outstanding performance of duties in support of the 1980 XIII Olympic Winter Games, Lake Placid, New York. Dr. Seth joined Lexicon in November 2014 as executive director of oncology marketing. As vice president of marketing, he will be responsible for leading the marketing efforts for telotristat ethyl while ensuring Lexicon's commercial readiness. Dr. Seth brings to Lexicon more than 20 years of experience, most recently at Eisai, Inc. where he served as executive director of Eisai value maximization systems and head of the oncology business unit. Before joining Eisai, Dr. Seth served in a series of marketing roles with Bristol-Myers Squibb, Pfizer and Schering-Plough involving products in oncology, cardiovascular and metabolic disease, immunology and central nervous system disorders. He received his Ph.D. from Meharry Medical College and MBA from St. Joseph's University and completed a Post Doctoral Fellowship at Harvard Medical School. Mr. Branch joined Lexicon in March 2016 with the responsibility of leading the sales effort for telotristat ethyl and building the sales function, including the sales team, sales operations, and sales training. He has over 24 years of commercial experience in the pharmaceutical industry with a deep breadth of experiences in both oncology and general pharmaceuticals including key roles as vice president of sales at GlaxoSmithKline Oncology, vice president of sales at Novartis Canada, and global brand director at Novartis Oncology. Prior to embarking on his career in the pharmaceutical industry, Gary served with distinction as captain in the U.S. Army, where he was awarded and recognized for performance in combat during Operations Desert Shield and Desert Storm. Gary has a BS degree in General Engineering from the United States Military Academy in West Point, NY, and an MBA from the University of Michigan Business School in Ann Arbor, MI. "I am very excited to be leading the commercial team at this crucial juncture, and look forward to making telotristat ethyl commercially available to carcinoid syndrome patients following regulatory approval," said Mr. Santini. "I look forward to working with the executive team to achieve our vision of developing and commercializing innovative medications to address the needs of patients, physicians, and payers."