NEW YORK, Nov. 16, 2016 /PRNewswire/ -- Even as kidney injury lawsuits involving Nexium and other proton pump inhibitors continue to mount in U.S. courts, new research is suggesting that the popular heartburn drugs could be associated with additional adverse health consequences. According to a study presented this week at the American Heart Association Scientific Sessions in New Orleans, proton pump inhibitors may increase an individual's risk for a first-time ischemic stroke.
For the study, researchers at the Danish Heart Foundation in Copenhagen analyzed medical records from nearly 245,000 Danish patients, average age 57, all of whom had undergone endoscopy to determine the cause of stomach pain and indigestion. Nearly 9,500 patients suffered their first ischemic stroke during the six-year follow-up. Overall, those using proton pump inhibitors were 21% more likely to suffer a stroke, with the highest doses associated with the highest risk. Certain proton pump inhibitors also appeared to increase the likelihood of a first-time ischemic stroke, with risk ranging from 30% for the highest dose of lansoprazole (Prevacid) to 94% for the highest dose of pantoprazole (Protonix). "This study only serves to highlight the potential dangers that may be associated with the widespread use of proton pump inhibitors. Additional research has linked these drugs to a higher risk of heart attacks and dementia, as well as a greater likelihood of chronic kidney disease, kidney failure, and other serious renal complications," says Sandy A. Liebhard, a partner at Bernstein Liebhard LLP. The Firm represents plaintiffs in proton pump inhibitor lawsuits involving chronic kidney disease, kidney failure, acute kidney injury, acute interstitial nephritis and other renal complications allegedly associated with use of the medications.