NORTHFIELD, Ill. and CHICAGO and ALEXANDRIA, Va., Nov. 14, 2016 /PRNewswire-USNewswire/ -- The College of American Pathologists (CAP), the American Society for Clinical Pathology (ASCP), and the American Society of Clinical Oncology (ASCO) today released an evidence-based clinical practice guideline on human epidermal growth factor receptor 2 (HER2) testing for patients with gastroesophageal cancers. " HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline from the College of American Pathologists, American Society for Clinical Pathology, and the American Society of Clinical Oncology" is now available as an early online release published in Archives of Pathology & Laboratory Medicine, American Journal of Clinical Pathology, and Journal of Clinical Oncology. The guideline provides recommendations about appropriate HER2 testing for patients at key decision points throughout their cancer therapy to determine if they are eligible for targeted therapy. Patients who are eligible for targeted therapy have additional treatment options available to them and they generally experience improved outcomes. Cancers of the stomach and esophagus are among the most common cancers globally, and an estimated 43,280 new cases of gastroesophageal adenocarcinoma (GEA) will be diagnosed in the US in 2016 1. Certain patients with advanced gastric cancer will have more HER2, known as an overexpression of HER2, than other patients. For those patients that overexpress HER2, the targeted therapy trastuzumab has been shown to improve patient survival when it is added to standard chemotherapy. "This guideline recommends that assessment of HER 2 status be included in the diagnostic protocol for gastroesophageal adenocarcinoma," explains Angela N. Bartley, MD, FCAP, a pathologist, St. Joseph Mercy Health System, Ann Arbor, Mich. "Ultimately, clinicians who use the guideline will help ensure that patients receive the best treatment for their type of cancer." Dr. Bartley represented the CAP and was one of the three organizational co-chairs of the international panel of pathology and oncology experts who developed the guideline. The panel's evidence-based process included extensive review of relevant published literature, feedback on draft guidance garnered through an open comment period earlier this year, and revisions based on that open commentary.