The second paper is titled " In vitro anti-neoplastic activity of specific phytocannabinoids of Cannabis sativa." As part of a more in-depth study to develop a cannabinoid-based targeted treatment of malignant tumors, the in vitro effects of select cannabinoids on several human cancer cell lines have been investigated, including glioblastoma, pancreatic, breast, melanoma, lung and colon. The paper describes how single-cell layer cultures were treated with increasing levels of a purified cannabinoid and details the resultant changes in cancer cell populations. Initial results suggest that this cannabinoid possesses potent anti-proliferative effects against several types of cancer cells. Studies continue to assess this cannabinoid with several cancer cell lines, and it may represent a viable candidate for further therapeutic evaluation.Dr. Hyslop has been involved in cancer research for four decades and is leading a team of scientists from UNC to develop a "green" approach to treating solid tumors, initially brain cancer. "We are looking forward to sharing some of our results with the scientific community," commented Dr. Hyslop. "Our team of biochemists, organic chemists, molecular biologists, genetic engineers, undergraduate students, and graduate students continue to work diligently to achieve our goal of developing targeted cannabinoid-based chemotherapy utilizing Cell-in-a-Box ®."
For more information on the meeting visit: https://www.acs.org/content/acs/en/meetings/spring-2017.html.About PharmaCyte BiotechPharmaCyte Biotech a clinical stage biotechnology company developing therapies for cancer and diabetes based upon a proprietary cellulose-based live cell encapsulation technology known as "Cell-in-a-Box ®." This technology will be used as a platform upon which therapies for several types of cancer and diabetes are being developed. PharmaCyte's therapy for cancer involves encapsulating genetically engineered human cells that convert an inactive chemotherapy drug into its active or "cancer-killing" form. These encapsulated cells are implanted as close to the patient's cancerous tumor as possible. Once implanted, a chemotherapy drug that is normally activated in the liver (ifosfamide) is given intravenously at one-third the normal dose. The ifosfamide is carried by the circulatory system to where the encapsulated cells have been implanted. When the ifosfamide comes in contact with the encapsulated cells they act as an artificial liver and activate the chemotherapy drug at the source of the cancer. This "targeted chemotherapy" has proven effective and safe to use in past clinical trials and results in no side effects. In addition to developing a novel therapy for cancer, PharmaCyte is developing a treatment for Type 1 diabetes and insulin-dependent Type 2 diabetes. PharmaCyte plans to encapsulate a human cell line that has been genetically engineered to produce, store and release insulin in response to the levels of blood sugar in the human body. The encapsulation will be done using the Cell-in-a-Box ® technology. Once the encapsulated cells are implanted in a diabetic patient they will function as a "bio-artificial pancreas" for purposes of insulin production.
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Investor Relations:PharmaCyte Biotech, Inc.Investor Relations DepartmentTelephone: 917.595.2856Email: Info@PharmaCyte.com