- All eyes had IOP = 18 mm Hg and 67% of eyes had IOP = 15 mm Hg without medication vs. preoperative unmedicated IOP between 22-38 mm Hg.
- Mean unmedicated IOP was 14.2 mm Hg, a 42% reduction from preoperative mean unmedicated IOP of 24.4 mm Hg; this reduction was maintained through 18 months.
Glaukos Corporation (NYSE: GKOS), an ophthalmic medical technology company focused on the development and commercialization of breakthrough products and procedures designed to transform the treatment of glaucoma, today announced that in a study published in Advances in Therapy, 100% of 57 phakic eyes with open-angle glaucoma achieved a = 20% reduction in unmedicated intraocular pressure (IOP) one year after implantation of the iStent inject ® Trabecular Micro-Bypass in a standalone procedure. Phakic refers to eyes that have not undergone prior cataract surgery and have a natural lens. The iStent inject is a second-generation Micro-Invasive Glaucoma Surgery (MIGS) device that includes two stents preloaded into an auto-injection mechanism. It allows an ophthalmic surgeon to inject the stents from within the eye's anterior chamber through the trabecular meshwork and into Schlemm's canal, the eye's drainage canal. Once in place, the stents are designed to reduce IOP by restoring the natural outflow pathways for aqueous humor. The study was conducted at a single international site, where 11 surgeons performed the 57 iStent inject procedures. Study researchers reported a high safety profile and plan to follow subjects through five years. Additional study findings at one year postoperative included: