Cellectis Announces Two Oral Presentations And One Poster At The 2016 ASH Annual Meeting

Regulatory News:

Cellectis (Paris:ALCLS) (NASDAQ:CLLS) (Alternext: ALCLS; Nasdaq: CLLS), a biopharmaceutical company focused on developing immunotherapies based on gene edited CAR T-cells (UCART), today announced that abstracts regarding the Company's allogeneic, off-the-shelf, CAR T programs have been accepted for presentation at the 58th American Society of Hematology (ASH) Annual Meeting and Exposition. The meeting will be held December 3-6, 2016 in San Diego.

Oral presentations:

Acute Myeloid Leukemia: Novel Therapy, excluding TransplantationProgram: Oral and Poster AbstractsType: OralSession: 616. Acute Myeloid Leukemia: Novel Therapy, excluding Transplantation: Emerging Immune-Based Therapies for AML Monday, December 5, 2016: 11:00 AM San Diego Ballroom AB (Marriott Marquis San Diego Marina)

Monica L. Guzman, PhD 1 , Mayumi Sugita, MD 1* , Hongliang Zong, MD, PhD 1* , Nathan Ewing-Crystal 1* , Vicenta Trujillo-Alonso 1* , Nuria Mencia-Trinchant, PhD 1* , Linda Lam 1* , Nicole M. Cruz, MD 1 , Roman Galetto, PhD 2* , Agnès Gouble, PhD 2* , Duane C Hassane, PhD 1 , Julianne Smith, PhD 2 and Gail J. Roboz 3 1 Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY 2 Cellectis SA, Paris, France 3 Weill Cornell Medical College, New York, NY

Myeloma: Pathophysiology and Pre-Clinical Studies, excluding TherapyProgram: Oral and Poster AbstractsType: OralSession: 652. Myeloma: Pathophysiology and Pre-Clinical Studies, excluding Therapy: Novel Immune Approaches for Myeloma Therapy Sunday, December 4, 2016: 12:30 PM Grand Hall B (Manchester Grand Hyatt San Diego)

Bijan Boldajipour, PhD 1* , Roman Galetto, PhD 2* , Cesar Sommer, PhD 1* , Thomas Pertel, PhD 1* , Julien Valton, PhD 3* , Yoon Park, PhD 1* , Annabelle Gariboldi 2* , Amy Chen 1* , Tao Geng 1* , Hong H Dong 1* , Gregory R Boucher 1* , Thomas J Van Blarcom, PhD 1* , Javier Chaparro-Riggers, PhD 1* , Arvind Rajpal, PhD 1* , Julianne Smith, PhD 3 , Tracy Kuo, PhD 1* and Barbra Sasu, PhD 1 1 Pfizer Inc., South San Francisco, CA 2 Cellectis SA, Paris, France 3 Cellectis Inc., New York, NY

Poster presentation:

Acute Myeloid Leukemia: Novel Therapy, excluding TransplantationProgram: Oral and Poster AbstractsSession: 616. Acute Myeloid Leukemia: Novel Therapy, excluding Transplantation: Poster III Monday, December 5, 2016, 6:00 PM-8:00 PM Hall GH (San Diego Convention Center)

Tianyu Cai, PhD 1* , Roman Galetto, PhD 2* , Agnès Gouble, PhD 2* , Julianne Smith, PhD 2 , Antonio Cavazos, MS 1* , Sergej Konoplev, MD, PhD 3 , Andrew A. Lane, MD, PhD 4 , Monica L. Guzman, PhD 5 , Hagop M. Kantarjian, MD 1 , Naveen Pemmaraju, MD 1 and Marina Konopleva, MD, PhD 1 1 Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 2 Cellectis SA, Paris, France 3 Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 4 Dana-Farber Cancer Institute, Boston, MA 5 Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medical College, New York, NY

About Cellectis

Cellectis is a biopharmaceutical company focused on developing immunotherapies based on gene edited CAR T-cells (UCART). The company's mission is to develop a new generation of cancer therapies based on engineered T-cells. Cellectis capitalizes on its 16 years of expertise in genome engineering - based on its flagship TALEN® products and meganucleases and pioneering electroporation PulseAgile technology - to create a new generation of immunotherapies. CAR technologies are designed to target surface antigens expressed on cells. Using its life-science-focused, pioneering genome-engineering technologies, Cellectis' goal is to create innovative products in multiple fields and with various target markets.

In June 2014, Cellectis and Pfizer began collaborating on a joint clinical development program for CAR-T therapies, in the field of oncology, directed at numerous targets selected by Pfizer.

Cellectis is listed on the Nasdaq market (ticker: CLLS) and on the NYSE Alternext market (ticker: ALCLS). To find out more about us, visit our website: www.cellectis.com

Talking about gene editing? We do it. TALEN® is a registered trademark owned by the Cellectis Group.

Disclaimer

This press release and the information contained herein do not constitute an offer to sell or subscribe, or a solicitation of an offer to buy or subscribe, for shares in Cellectis in any country. This press release contains forward-looking statements that relate to the Company's objectives based on the current expectations and assumptions of the Company's management only and involve risk and uncertainties that could cause the Company to fail to achieve the objectives expressed by the forward-looking statements above.

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