HONG KONG, Nov. 1, 2016 /PRNewswire/ -- In the United States alone, an estimated 15 million fractures occurs annually, including 1.6 million hospital admissions for traumatic fractures and 2 million osteoporotic fractures, costing over 60 billion dollars and calling for 1.6 million bone grafts each year; a growing demand for bone grafts is similarly observed worldwide. Bone is the second most commonly implanted material in the human body, after blood transfusion. The science of bone grafts in nonunion and bone loss have been established and refined, and new methods of bone graft extraction that limits pain and complications for these treatments should be determined, developed and implemented for the minimally invasive treatment advantages. A passive and effortless percutaneous method providing full control and precision for the endeavor would be supreme. A "Bone Graft" is the basic ingredient and the basis of almost every major reconstructions for many orthopedic and spinal disorders which include deformities, degeneration, fractures and damages. Degenerative Disc Disease (DDD) commonly known as 'slipped disc', scoliosis, spondylolisthesis, spinal stenosis, and vertebral fractures all require a spinal fusion treatment using a "Bone Graft". According to the WHO Low Back Pain (LBC) is the number 1 cause of disability worldwide, and together with the treatments for severe neck pain, nonunion fractures of long bones, cranial maxillofacial fractures commonly consequent to automobile accidents and so on, they all firstly require a "Bone Graft" to repair the patient. Without a "Bone Graft", none of all these conditions can be suitably treated. The increased prevalence of spinal fusion surgery alone has created an industry focus on bone graft alternatives. While autologous bone graft, also known as autograft - the patient's own solid living bone tissue usually extracted from the hips remains the gold standard, but the pain and complications from extracting autologous bone graft, the problems with open surgery extraction drives the endless search for a reliable and safe bone graft substitute product. Many approaches are used in the repair of skeletal defects in reconstructive orthopedic surgery, and bone grafting is involved in virtually every procedure. Autografting (live bone extracted from the patient) remains the gold standard for replacing bone loss. Moreover most alternatives, including bone bank which bear contamination, artificial discs and stem cell products are expensive and mostly not compatible nor validated by Evidence based medicine EBM, thus being scarcely recommendable for clinical use. The search for alternative biomaterials for a bone graft continues.