As part of your daily routine as an active trader or investor, it's important to track the stocks in the market that are making the biggest percentage gains and the biggest percentage losses.

Stocks that are making large moves to the upside are favorites among short-term traders who want to capture some of that massive volatility. Stocks that are making big-percentage moves are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside.

Titan Pharmaceuticals

  • Tuesday's Range: $5.00-$5.40
  • 52-Week Range: $2.49-$10.00
  • Tuesday's Volume: 152,000
  • Three-Month Average Volume: 48,681

Titan Pharmaceuticals  (TTNP - Get Report) , a specialty pharmaceutical company, develops proprietary therapeutics for the treatment of serious medical disorders in the U.S. This stock traded up 1.9% to $5.30 in Tuesday's trading session.

From a technical perspective, Titan Pharmaceuticals spiked modestly higher here and showed relative strength compared with the overall market weakness with strong upside volume flows. This stock has experienced a number of above-average volume days combined with share price strength over the last few weeks. This high-volume move to the upside on Tuesday is now quickly pushing shares of Titan Pharmaceuticals within range of triggering a major breakout trade above some key near-term overhead resistance levels. That breakout will trigger if this stock manages to take out some near-term overhead resistance levels at $5.44 to $5.62 a share with high volume.

Traders should now look for long-biased trades in Titan Pharmaceuticals as long as it's trending above its 20-day moving average of $4.54 or its 50-day moving average of $4.35 a share and then once it sustains a move or close above those breakout levels with volume that hits near or above 48,681 shares. If that breakout materializes soon, then this stock will set up to re-test or possibly take out its next major overhead resistance level at $10 a share.

Zafgen

  • Tuesday's Range: $5.94-$6.27
  • 52-Week Range: $5.43-$55.36
  • Tuesdays Volume: 793,000
  • Three-Month Average Volume: 1.27 million

Zafgen  (ZFGN) , a biopharmaceutical company, focuses on the development of therapeutics for patients suffering from obesity and obesity-related disorders. This stock traded up 2.3% to $6.12 in Tuesday's trading session.

From a technical perspective, Zafgen trended modestly higher on Tuesday and showed relative strength versus the overall market weakness with lighter-than-average volume. This stock recently gapped-down sharply lower from over $17 to under $7 a share with heavy downside volume flows. Following that move, shares of Zafgen went on to tag a new a new all-time low at $5.43 a share. This stock has now started to spike a bit higher above that $5.43 low and it's beginning to move within range of triggering a major breakout trade. That trade will trigger if this stock manages to take out some near-term overhead resistance levels at Tuesday's intraday high of $6.28 to its gap-down-day high of $6.95 a share with high volume.

Traders should now look for long-biased trades in Zafgen as long as it's trending above Tuesday's intraday low of $5.94 or above its all-time low of $5.43 a share and then once it sustains a move or close above those breakout levels with volume that hits near or above 1.27 million shares. If that breakout triggers soon, then this stock will set up to re-fill some of its recent gap-down-day zone that started near $17 a share.

Synergy Pharmaceuticals

  • Tuesday's Range: $5.80-$6.33
  • 52-Week Range: $2.75-$10.15
  • Tuesday's Volume: 1.67 million
  • Three-Month Average Volume: 2.16 million

Synergy Pharmaceuticals  (SGYP) , a biopharmaceutical company, focuses on the development of drugs to treat gastrointestinal disorders and diseases. This stock traded up 5.5% to $6.24 in Tuesday's trading session.

From a technical perspective, Synergy Pharmaceuticals ripped sharply higher on Tuesday right off some near-term support at $5.80 a share with decent upside volume flows. This stock has been consolidating and trending sideways over the last two months and change, with shares moving between $5.50 on the downside and just over $7 a share on the upside. This spike higher on Tuesday has started to push shares of Synergy Pharmaceuticals back above both its 20-day moving average of $6.12 a share and its 50-day moving average of $6.14 a share. This move is now quickly pushing this stock within range of triggering a big breakout trade above the upper-end of its recent sideways trending chart pattern. That trade will trigger if this stock manages to take out some near-term overhead resistance levels at $6.58 to $6.97 and then above more resistance at $7.15 a share with high volume.

Traders should now look for long-biased trades in Synergy Pharmaceuticals as long as it's trending above some near-term support at $5.80 or above more support at $5.50 a share and then once it sustains a move or close above those breakout levels with volume that hits near or above 2.16 million shares. If that breakout gets started soon, then this stock will set up to re-test or possibly take out its next major overhead resistance levels at $7.72 to $7.93, or even $8.50 to $9 a share.

Natera

  • Tuesday's Range: $9.53-$10.17
  • 52-Week Range: $7.74-$23.24
  • Tuesday's Volume: 76,000
  • Three-Month Average Volume: 224,273

Natera  (NTRA - Get Report) , a genetic testing company, develops and commercializes non-invasive methods for analyzing deoxyribonucleic acid in the U.S. and Europe. This stock traded up 2.2% to $9.92 in Tuesday's trading session.

From a technical perspective, Natera jumped a bit higher here right above both its 50-day moving average of $9.12 and its 20-day moving average of $9.24 a share with lighter-than-average volume. This stock has been uptrending strong over the last month and change, with shares moving higher from its low of $7.74 to its intraday high on Tuesday of $10.17 a share. During that uptrend, shares of Natera have been making mostly higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of Natera within range of triggering a big breakout trade above some key near-term overhead resistance levels. That breakout will trigger if this stock manages to clear Tuesday's intraday high of $10.17 and then once it takes out more near-term resistance levels at $10.80 to $11 a share with high volume.

Traders should now look for long-biased trades in Natera as long as it's trending above its 50-day moving average of $9.12 or above more near-term support at $8.78 a share and then once it sustains a move or close above those breakout levels with volume that hits near or above 224,273 shares. If that breakout hits soon, then this stock will set up to re-test or possibly take out its next major overhead resistance levels at $12 to $13 a share.

Disclosure: This article is commentary by an independent contributor. At the time of publication, the author held no positions in the stocks mentioned.