DELAFIELD, Wis. (Stockpickr) -- As part of your daily routine as an active trader or investor, it's important to track the stocks in the market that are making the biggest percentage gains and the biggest percentage losses.

Stocks that are making large moves to the upside are favorites among short-term traders who want to capture some of that massive volatility. Stocks that are making big-percentage moves are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside.

MannKind

MNKD ChartMNKD data by YCharts

MannKind (MNKD - Get Report), a biopharmaceutical company, focuses on the discovery, development and commercialization of therapeutic products for diabetes in the U.S. This stock is trading up 4.1% to $5.72 share in Thursday's trading session.

Thursday's Range: $5.53-$5.80
52-Week Range: $3.46-$10.10
Thursday's Volume: 2.60 million
Three-Month Average Volume: 7.96 million

From a technical perspective, MannKind is ripping sharply higher here right off both its 200-day moving average of $5.58 and its 20-day moving average of $5.60 with lighter-than-average volume. This stock has been uptrending a bit over the last few weeks, with shares moving higher from its low of $5 to its intraday high on Thursday of $5.80. During that move, shares of MannKind have been consistently making higher lows and higher highs, which is bullish technical price action. This spike higher in the stock here is now starting to push MannKind within range of triggering a near-term breakout trade. That trade will hit if this stock manages to take out some key near-term overhead resistance levels at $6 to $6.07 and then above more key resistance at $6.25 with high volume.

Traders should now look for long-biased trades in MannKind as long as it's trending above its 200-day at $5.58 or above its 50-day at $5.27 and then once it sustains a move or close above those breakout levels with volume that registers near or above 7.96 million shares. If that breakout takes hold soon, then this stock will set up to re-test or possibly take out its next major overhead resistance levels at $7 to $7.32 a share, or even $7.50 to $7.88 a share.

Pernix Therapeutics

PTX ChartPTX data by YCharts

Pernix Therapeutics (PTX), a specialty pharmaceutical company, develops, manufactures, markets and sells branded and generic pharmaceutical products. This stock is trading up 10.5% to $6.07 in Thursday's trading session.

Thursday's Range: $5.53-$6.07
52-Week Range: $5.06-$12.88
Thursday's Volume: 1.14 million
Three-Month Average Volume: 1.44 million

From a technical perspective, Pernix Therapeutics is exploding sharply higher here right off its 20-day moving average of $5.63 with strong upside volume flows. This stock recently carved out a major bottoming chart pattern, after shares founding buying interest after coming out of a large downtrend at $5.06, $5.44 and $5.29 a share. Shares of Pernix Therapeutics are now quickly spiking within range of triggering a major breakout trade above some key near-term overhead resistance levels. That breakout will trigger if this stock manages to clear some major near-term overhead resistance levels at its 50-day moving average of $6.06 and then above more resistance at $6.17 to $6.29 with high volume.

Traders should now look for long-biased trades in Pernix Therapeutics as long as it's trending above some key near-term support at $5.50 and then once it sustains a move or close above those breakout levels with volume that hits near or above 1.44 million shares. If that breakout materializes soon, then this stock will set up to re-test or possibly take out its next major overhead resistance levels at $6.70 to $7.10, or even $7.50 to $8 a share.

Calithera Biosciences

CALA ChartCALA data by YCharts

Calithera Biosciences CALA, a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule drugs directed against tumor metabolism and tumor immunology targets for the treatment of cancer in the U.S. This stock is trading up 2.4% to $7.05 in Thursday's trading session.

Thursday's Range: $6.82-$7.18
52-Week Range: $6.51-$33.48
Thursday's Volume: 203,000
Three-Month Average Volume: 503,176

From a technical perspective, Calithera Biosciences is spiking notably higher here right above some key near-term support at $7 with lighter-than-average volume. This stock has been attempting to carve out a major bottoming chart pattern over the last month and change, with shares finding buying interest at $6.75, $6.61 and $6.60 a share. That bottom attempt is coming after shares of Calithera Biosciences downtrended badly off its March high of $22 to its recent low of $6.60 a share.

This stock is now starting to spike off those recent support levels, and it's beginning to trend within range of triggering a major breakout trade. That breakout will trigger if this stock manages to take out some near-term overhead resistance levels at its 20-day moving average of $7.34 and then above more resistance at $7.40 to $7.54 with high volume.

Traders should now look for long-biased trades in Calithera Biosciences as long as it's trending above $7 or above its recent low of $6.60 and then once it sustains a move or close above those breakout levels with volume that hits near or above 503,176 shares. If that breakout triggers soon, then this stock will set up to re-test or possibly take out its next major overhead resistance levels at $9 to $9.69 a share.

Synthesis Energy

SYMX ChartSYMX data by YCharts

Synthesis Energy (SYMX), a development stage energy and gasification technology company, provides various proprietary gasification technology systems and solutions to the energy and chemical industries worldwide. This stock is trading up 6.6% to $1.60 in Thursday's trading session.

Thursday's Range: $1.46-$1.63
52-Week Range: $0.63-$2.10
Thursday's Volume: 689,000
Three-Month Average Volume: 1.10 million

From a technical perspective, Synthesis Energy is ripping sharply higher here right off its 20-day moving average of $1.46 with strong upside volume flows. This stock has been uptrending over the last two months and change, with shares moving higher from its low of $1.20 to its recent high of just over $1.70 a share. During that uptrend, shares of Synthesis Energy have been consistently making higher lows and higher highs, which is bullish technical price action.

This large spike to the upside on Thursday is now quickly pushing this stock within range of triggering a major breakout trade. That breakout will trigger if shares of Synthesis Energy manages to take out some key near-term overhead resistance around $1.70 with high volume.

Traders should now look for long-biased trades in Synthesis Energy as long as it's trending above its 20-day at $1.46 or its 50-day at $1.41 and then once it sustains a move or close above $1.70 with volume that hits near or above 1.10 million shares. If that breakout gets set off soon, then this stock will set up to re-test or possibly take out its next major overhead resistance levels at $2.02 to its 52-week high of $2.10.

This article is commentary by an independent contributor. At the time of publication, the author held no positions in the stocks mentioned.