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NEW YORK (TheStreet) -- If you're in a dogfight to attract customers, your customers might win, but your shareholders certainly won't. That was what Jim Cramer's told his Mad Money viewers Wednesday after the transportation stocks, led by the airlines, pulled the averages lower.

When the CEO of American Airlines (AAL) appeared on Mad Money last night, he told investors that competition is starting to heat up and American is ready to respond with lower fares if needed. That spells trouble for the entire airline industry, Cramer warned, because the earnings estimates for the airlines will need to be cut.

That's why Cramer suggested sticking with companies that have no competition, companies like the biotechs, which often have proprietary drugs protected by patents or orphan drug status. His favorites among the group were Regeneron (REGN) and United Therapeutics (UTHR), whose CEO also appeared on last night's show.

Cramer was also bullish on Target (TGT), a stock he owns for his charitable trust, Action Alerts PLUS, as that company has competition but is crushing it.

Also on the "no competition" list was natural and organic food makers Hain Celestial (HAIN) and WhiteWave Foods (WWAV) plus Apple (AAPL), the latter two also Action Alerts PLUS names.

Executive Decision: Strauss Zelnick

For his "Executive Decision" segment, Cramer sat down with Strauss Zelnick, chairman and CEO of Take-Two Interactive (TTWO), the video game maker that just delivered a 22-cents-a-share earnings beat and boosted its stock buyback program after another strong quarter.

Zelnick said Take-Two is not just a hit-driven company, it's a solidly profitable company with a diverse lineup of titles that they're working hard to build into permanent franchises. That's why Take-Two doesn't release new versions of their games annually, outside of sports titles, and instead takes some time to build the next installments with compelling stories and interactivity.

When asked about Asian markets, Zelnick said that after entering Asia just a few years ago, the Asian market is now a big contributor to Take-Two's growth targets.

With Take-Two continuing to ride the current edge of interactive entertainment, Cramer said this is one company investors should consider.

Brake for Fiat Chrysler

There's a shining star in the auto industry, Cramer told viewers, but chances are investors aren't even paying attention. That star is Fiat Chrysler (FCAU), a stock that's only been trading in the U.S. since October but is already up 36% so far in 2015.

Most investors stopped following Chrysler after the company filed for bankruptcy in 2009. But in 2014 the European-based Fiat bought the rest of Chrysler that it didn't already own and launched a successful IPO late last year at $9 share.

The new Fiat Chrysler consists of a stable of U.S. brands, like Chrysler, Jeep, Dodge and Ram, but also a host of higher-end European stalwarts including Alfa Romeo, Ferrari and Maserati.

While most U.S. automakers bemoaned the currency pressures of the strong U.S. dollar, Fiat Chrysler, which is based in Europe but still has two-thirds of its sales in the U.S., had the opposite problem -- revenue that were skyrocketing.

Those windfall profits may wane a bit as the dollar weakens, but the fact remains that Fiat Chrysler is seeing great sales, with Jeep sales up 22%, Europe turning profitable and the company regaining the number one automaker spot in Brazil.

Executive Decision: Marc Benioff

In his second "Executive Decision" segment, Cramer spoke with Marc Benioff, chairman and CEO of Salesforce.com (CRM), which today delivered a 2-cents-a-share earnings beat that sent shares up 6%.

Benioff reiterated he's building a company not just focused on shareholders but on all stakeholders, including employees and the communities it's based in. He noted that 1% of Salesforce's profits flow into its charitable foundation, which to date has provided over one million hours of community service.

When asked about the myriad of takeover rumors, Benioff said he's focused on becoming the fastest company to reach $10 billion in sales and spends his time talking to customers and helping to make them successful.

Companies want to do business with a company they trust, Benioff concluded, and that's why he hasn't been distracted by rumors and is doing right by all their stakeholders instead.

Lightning Round

In the Lightning Round, Cramer was bullish on Flextronics (FLEX) and LyondellBasell Industries (LYB).

Cramer was bearish on Halyard Health (HYH).

No Huddle Offense

In his "No Huddle Offense" segment, Cramer said that population growth is the only real way to spur economic growth, and nowhere was that more evident than in Home Depot's (HDconference call this quarter.

One of the key components to Home Depot's business is new household formation, a number that was cut in half during the great recession as more and more children opted to live at home with their parents than try to get a mortgage of their own.

But now household formation appears to be on the mend, and that's great news for everything related to housing. Other factors include employment, which is getting better, salaries, which are not, student loan debt, which is getting worse, and the availability of credit, which is slowly on the mend.

The only way to really get a non-Federal Reserve inspired economic recovery, however, is by having more families that need more homes, Cramer concluded, and with that finally starting to happen, Home Depot could be on the verge of a big uptrend.

To watch replays of Cramer's video segments, visit the Mad Money page on CNBC.

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At the time of publication, Cramer's Action Alerts PLUS had a position in AAPL, HYH, TGT and WWAV.

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