DELAFIELD, Wis. (Stockpickr) -- As part of a daily routine as an active trader or investor, one should always be tracking the stocks in the market that are making the biggest percentage gains and the biggest percentage losses.

Stocks that are making large moves to the upside are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside.

Arrowhead Research

Arrowhead Research (ARWR - Get Report) develops novel drugs to treat intractable diseases in the U.S. This stock is trading up 4.5% to $7.77 in Thursday's trading session.

Thursday's Range: $7.21-$7.86
52-Week Range: $4.95-$18.64
Thursday's Volume: 1.06 million
Three-Month Average Volume: 1.94 million

From a technical perspective, ARWR is ripping higher here right above its 50-day moving average of $7.09 with strong upside volume flows. This spike to the upside is now quickly pushing shares of ARWR within range of triggering a major breakout trade above some key near-term overhead resistance levels. That trade will trigger if ARWR manages to take out some near-term overhead resistance levels at $7.90 to $8.36 with high volume.

Traders should now look for long-biased trades in ARWR as long as it's trending above its 50-day moving average of $7.09 and then once it sustains a move or close above those breakout levels with volume that hits near or above 1.94 million shares. If that breakout triggers soon, then ARWR will set up to re-test or possibly take out its next major overhead resistance levels at $8.36 to $9.33, or even its 200-day moving average of $9.44.

Venaxis

Venaxis (APPY) develops and commercializes products for unmet diagnostic and therapeutic needs. This stock is trading up 8.1% to 50 cents per share in Thursday's trading session.

Thursday's Range: $0.46-$0.51
52-Week Range: $0.40-$2.53
Thursday's Volume: 616,000
Three-Month Average Volume: 700,726

From a technical perspective, APPY is ripping higher here right above some near-term support at 43 cents per share with decent upside volume flows. This strong move to the upside on Thursday is now quickly pushing shares of APPY within range of triggering a big breakout trade above some key near-term overhead resistance levels. That trade will hit if APPY manages to take out some key near-term overhead resistance levels at 52 to 54 cents per share with high volume.

Traders should now look for long-biased trades in APPY as long as it's trending above Thursday's intraday low of 45 cents per share and then once it sustains a move or close above those breakout levels with volume that hits near or above 700,726 shares. If that breakout begins soon, then APPY will set up to re-test or possibly take out its next major overhead resistance levels at 60 to 64 cents per share. Any high-volume move above 65 cents per share will then give APPY a chance to re-fill some of its previous gap-down-day zone from January that started at $2 a share.

A.M. Castle

A.M. Castle (CAS), together with its subsidiaries, operates as a specialty metals and plastics distribution company in the U.S., Canada, Mexico, France, the U.K., Spain, China and Singapore. This stock is trading up 4.4% to $4.44 in Thursday's trading session.

Thursday's Range: $3.47-$3.70
52-Week Range: $2.80-$14.95
Thursday's Volume: 65,000
Three-Month Average Volume: 309,613

From a technical perspective, CAS is spiking notably higher here right above some near-term support at $3.44 with lighter-than-average volume. this stock has been uptrending over the last month and change, with shares moving higher from its low of $2.80 to its recent high of $4.09. During that uptrend, shares of CAS have been making mostly higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of CAS within range of triggering a big breakout trade above some key near-term overhead resistance levels. That trade will trigger if CAS manages to take out some key near-term overhead resistance levels at $3.71 to $4.09 with high volume.

Traders should now look for long-biased trades in CAS as long as it's trending above some near-term support at $3.44 and then once it sustains a move or close above those breakout levels with volume that hits near or above 309,613 shares. If that breakout develops soon, then CAS will set up to re-test or possibly take out its next major overhead resistance levels at $4.50 to its 50-day moving average of $4.72.

This article is commentary by an independent contributor. At the time of publication, the author held no positions in the stocks mentioned.