DELAFIELD, Wis. (Stockpickr) -- Professional traders running mutual funds and hedge funds don't just look at a stock's price moves; they also track big changes in volume activity. Often when above-average volume moves into an equity, it precedes a large spike in volatility.

Major moves in volume can signal unusual activity, such as insider buying or selling -- or buying or selling by "superinvestors."

Unusual volume can also be a major signal that hedge funds and momentum traders are piling into a stock ahead of a catalyst. These types of traders like to get in well before a large spike, so it's always a smart move to monitor unusual volume. That said, remember to combine trend and price action with unusual volume. Put them all together to help you decipher the next big trend for any stock.

With that in mind, let's take a look at several stocks rising on unusual volume recently.

Ingles Markets

Ingles Markets  (IMKTA - Get Report) operates various supermarkets in the southeast U.S. This stock is trading up 7.1% to $46.31 in Monday's trading session.

Monday's Volume: 192,000
Three-Month Average Volume: 168,149
Volume % Change: 130%

From a technical perspective, IMKTA is ripping sharply higher here right above its 50-day moving average of $41.51 and its breaking out above some near-term overhead resistance at $44.98 with high volume. This strong spike to the upside on Monday is now quickly pushing shares of IMKTA within range of triggering a much bigger breakout trade above some key near-term overhead resistance levels. That trade will hit if IMKTA manages to clear Monday's intraday high of $46.87 and then once it takes out its 52-week high of $48.30 with high volume.

Traders should now look for long-biased trades in IMKTA as long as it's trending above Monday's intraday low of $43.86 or above its 50-day at $41.51 and then once it sustains a move or close above those breakout levels with volume that hits near or above 168,149 shares. If that breakout gets underway soon, then IMKTA will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $55 to $60.

La Jolla Pharmaceutical

La Jolla Pharmaceutical  (LJPC - Get Report), a biopharmaceutical company, focuses on the discovery, development and commercialization of therapeutics for chronic organ failure and cancer. This stock is trading up 4.9% to $21.33 in Monday's trading session.

Monday's Volume: 207,000
Three-Month Average Volume: 193,715
Volume % Change: 125%

From a technical perspective, LJPC is spiking higher here right above its 50-day moving average of $19.18 with above-average volume. This stock has been uptrending a bit over the last month, with shares moving higher from its low of $16.82 to its intraday high of $22. During that uptrend, shares of LJPC have been consistently making higher lows and higher highs, which is bullish technical price action. That uptrend has also been developing while shares of LJPC have bounced off and held its 50-day moving average over that timeframe. This stock is now starting to trend within range of triggering a big breakout trade. That trade will hit if LJPC manages to take out its 52-week high of $22.80 with high volume.

Traders should now look for long-biased trades in LJPC as long as it's trending above its 50-day moving average of $19.18 and then once it sustains a move or close above its 52-week high of $22.80 with volume that registers near or above 193,715 shares. If that breakout develops soon, then LJPC will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $25 to $30.

Carnival

Carnival  (CUK) operates as a cruise company. This stock is trading up 1.6% at $45.83 in Monday's trading session.

Monday's Volume: 405,000
Three-Month Average Volume: 324,959
Volume % Change: 192%

From a technical perspective, CUK is trending modestly higher here right off its 50-day moving average of $44.91 with above-average volume. This trend to the upside on Monday is now starting to push shares of CUK within range of triggering a major breakout trade above some key near-term overhead resistance levels. That trade will hit if CUK manages to take out some near-term overhead resistance levels at $45.75 and then above its 52-week high of $47.23 with high volume.

Traders should now look for long-biased trades in CUK as long as it's trending above some near-term support levels at $44 or at $43.06 and then once it sustains a move or close above those breakout levels with volume that hits near or above 324,959 shares. If that breakout triggers soon, then CUK will set up to enter new 52-week-high territory above $47.23, which is bullish technical price action. Some possible upside targets off that breakout are $50 to $55.

Jazz Pharmaceutical

Jazz Pharmaceutical  (JAZZ - Get Report), a biopharmaceutical company, identifies, develops and commercializes pharmaceutical products for various medical needs in the U.S., Europe and internationally. This stock is trading up 3% to $175.14 in Monday's trading session.

Monday's Volume: 592,000
Three-Month Average Volume: 670,484
Volume % Change: 164%

From a technical perspective, JAZZ is ripping to the upside here right above some near-term support at $169.72 and right above its 50-day moving average of $168.28 with decent upside volume flows. This spike to the upside on Monday is now starting to push shares of JAZZ within range of triggering a major breakout trade above some key near-term overhead resistance levels. That trade will hit if JAZZ manages to take out some near-term overhead resistance levels at $180.39 to its 52-week high of $183.84 with high volume.

Traders should now look for long-biased trades in JAZZ as long as it's trending above some near-term support at $169.72 or above its 50-day at $168.28 and then once it sustains a move or close above those breakout levels with volume that hits near or above 670,484 shares. If that breakout triggers soon, then JAZZ will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $190 to $200.

-- Written by Roberto Pedone in Delafield, Wis.

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This article is commentary by an independent contributor. At the time of publication, the author held no positions in the stocks mentioned.