DELAFIELD, Wis. (Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are the biggest percentage gainers and the biggest percentage losers.

Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade.

Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining with fundamental trends, discipline and sound money management, you will be well on your way to investment success.

With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside.

Alcobra

Alcobra (ADHD) , a biopharmaceutical company, focuses on the development and commercialization of proprietary drug candidates. This stock is trading up 5.9% to $7.33 in Tuesday's trading session.

Tuesday's Range: $6.95-$7.59
52-Week Range: $3.12-$25.44
Tuesday's Volume: 240,000
Three-Month Average Volume: 297,100

From a technical perspective, ADHD is ripping sharply higher here and breaking out above some near-term overhead resistance at $6.95 with strong upside volume flows. This spike to the upside on Tuesday is now quickly pushing shares of ADHD within range of triggering a much bigger breakout trade. That trade will hit if ADHD manages to take out some key near-term overhead resistance levels at $7.79 to its gap-down-day high from last October at $8 with high volume.

Traders should now look for long-biased trades in ADHD as long as it's trending above Tuesday's intraday low of $6.95 or above more near-term support at $6 and then once it sustains a move or close above those breakout levels with volume that registers near or above 297,100 shares. If that breakout hits soon, then ADHD will set up to re-fill some of its previous gap-down-day zone from last October that started near $16.

Atossa Genetics

Atossa Genetics (ATOS) operates as a health care company that focuses on the development of a suite of laboratory services, medical devices and therapeutics for breast cancer in the U.S. This stock is trading up 10.1% to $1.84 in Tuesday's trading session.

Tuesday's Range: $1.65-$1.85
52-Week Range: $0.80-$2.57
Tuesday's Volume: 734,000
Three-Month Average Volume: 758,718

From a technical perspective, ATOS is ripping sharply higher here right above some near-term support at $1.60 with strong upside volume flows. This stock recently gapped higher from around $1.20 to $1.86 with heavy upside volume. Shares of ATOS have continued to spike higher since that gap up and it's now quickly moving within range of triggering a major breakout trade. That trade will hit if ATOS manages to clear some key near-term overhead resistance at $1.96 to $2.10 with high volume.

Traders should now look for long-biased trades in ATOS as long as it's trending above Tuesday's intraday low of $1.65 or above $1.60 and then once it sustains a move or close above those breakout levels with volume that hits near or above 758,718 shares. If that breakout begins soon, then ATOS will set up to re-fill some of its previous gap-down-day zone from last September that started near $2.50. If that gap gets filled with volume, then ATOS could even tag or take out $3.

Arrowhead Research

Arrowhead Research (ARWR - Get Report) develops novel drugs to treat intractable diseases in the U.S. This stock is trading up 5.4% to $7.14 in Tuesday's trading session.

Tuesday's Range: $6.75-$7.25
52-Week Range: $4.95-$27.63
Tuesday's Volume: 874,000
Three-Month Average Volume: 2.50 million

From a technical perspective, ARWR is ripping sharply higher here right above its 50-day moving average of $6.54 with lighter-than-average volume. This stock has been carving out a major bottoming chart pattern over the last month and change, with shares finding buying interest each time it has pulled back to around $6 a share. Shares of ARWR are now starting to spike higher off those support levels and are quickly moving within range of triggering a major breakout trade. That trade will trigger if ARWR manages to clear some more key near-term overhead resistance levels at $7.28 to around $7.50 with high volume.

Traders should now look for long-biased trades in ARWR as long as it’s trending above its 50-day moving average of $6.54 or above major support at $6 and then once it takes out those breakout levels with volume that hits near or above 2.50 million shares. If that breakout gets started soon, then ARWR will set up to re-test or possibly take out its next major overhead resistance levels at $9.33 to its 200-day moving average of $10.20.

Sophiris Bio

Sophiris (SPHS) , a clinical-stage biopharmaceutical company, focuses on the research, development and commercialization of products for the treatment of urological diseases. This stock is trading up 3.7% to 46 cents per share in Tuesday's trading session.

Tuesday's Range: $0.44-$0.46
52-Week Range: $0.42-$4.08
Tuesday's Volume: 38,000
Three-Month Average Volume: 355,890

From a technical perspective, SPHS is trending higher here right above some near-term support at 43 cents per share with lighter-than-average volume. This stock has been trending sideways and consolidating for the last month and change, with shares moving between 42 cents per share on the downside and 50 cents per share on the upside. SPHS is now starting to bounce higher off the lower end of its range and moving close to triggering a big breakout trade above the upper end of its sideways trading chart pattern. That trade will hit if SPHS manages to take out some key near-term overhead resistance levels 48 cents to 49 cents per share and then above 50 cents per share with high volume.

Traders should now look for long-biased trades in SPHS as long as it's trending above its new 52-week low of 42 cents per share and then once it sustains a move or close above those breakout levels with volume that registers near or above 355,890 shares. If that breakout triggers soon, then SPHS will set up to re-test or possibly take out its next major overhead resistance level at 58 cents per share. Any high-volume move above 58 cents per share will then give SPHS a chance to re-fill some of its previous gap-down-day zone from last December that started just above $1.

-- Written by Roberto Pedone in Delafield, Wis.

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At the time of publication, author had no positions in stocks mentioned. Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.