Correction: This story was updated to disclose that Jim Cramer's Action Alerts PLUS is long Twitter.
NEW YORK ( TheStreet) -- Shares of Twitter ( TWTR) are higher by 1.5% on Monday, after JMP Securities initiated coverage of the stock with a "market outperform" rating and a $49 price target.
On CNBC's "Mad Dash" segment, Jim Cramer, co-manager of the Action Alerts PLUS portfolio, which holds shares of Twitter, said the stock would outperform, if the company was better managed.
Despite Twitter's 284 million monthly active users, the stock is down 9% in the past three months and 40% for the year.
TheStreet's Cramer said Twitter generates advertisement loads of just 1.3%, while its peers generate two to three times that amount.
If the company was managed more efficiently, the stock would really start to move higher. There is "a lot of upside," Cramer said.
Opko Health sold the rights to the drug for an upfront payment of $295 million, with the potential for another $275 million in regulatory milestone payments.
Shares of Opko Health, which has a market capitalization of $3.5 billion, are higher by about 9.3% in response.