DELAFIELD, Wis. (Stockpickr) -- Professional traders running mutual funds and hedge funds don't just look at a stock's price moves; they also track big changes in volume activity. Often when above-average volume moves into an equity, it precedes a large spike in volatility.

Major moves in volume can signal unusual activity, such as insider buying or selling -- or buying or selling by "superinvestors."

Unusual volume can also be a major signal that hedge funds and momentum traders are piling into a stock ahead of a catalyst. These types of traders like to get in well before a large spike, so it's always a smart move to monitor unusual volume. That said, remember to combine trend and price action with unusual volume. Put them all together to help you decipher the next big trend for any stock.

With that in mind, let's take a look at several stocks rising on unusual volume recently.

NetEase

NetEase (NTES) , through its subsidiaries, operates in online games, Internet portal and e-mail and wireless value-added services businesses in the People's Republic of China. This stock closed up 3.6% to $88.99 in Wednesday's trading session.

Wednesday's Volume: 1.13 million
Three-Month Average Volume: 389,605
Volume % Change: 203%

From a technical perspective, NTES counter-trended notably higher here back above its 50-day moving average of $86.47 with strong upside volume flows. This move pushed shares of NTES into breakout territory, since the stock took out some near-term overhead resistance at $86.88. Shares of NTES are now quickly moving within range of triggering another big breakout trade. That trade will hit if NTES manages to take out some key near-term overhead resistance levels at $90.08 to its 52-week high of $91.06 with high volume.

Traders should now look for long-biased trades in NTES as long as it's trending above its 50-day at $86.47 or above Wednesday's intraday low of $83.87 and then once it sustains a move or close above those breakout levels with volume that hits near or above 389,605 shares. If that breakout begins soon, then NTES will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $95 to $100.

Synageva BioPharma

Synageva BioPharma (GEVA) operates as a biopharmaceutical company in the U.S.. It focuses on the discovery, development and commercialization of therapeutic products for patients with rare diseases. This stock closed up 7.4% at $71.13 in Wednesday's trading session.

Wednesday's Volume: 576,000
Three-Month Average Volume: 267,011
Volume % Change: 85%

From a technical perspective, GEVA ripped sharply higher here right above some near-term support at $63.42 and back above its 50-day moving average of $68.27 with above-average volume. This relative strength to the upside on Wednesday also pushed shares of GEVA into breakout territory, since the stock took out some key near-term overhead resistance levels at $69.17 to $70. Market players should now look for a continuation move higher in the near-term if shares of GEVA manage to clear Wednesday's intraday high of $71.82 with high volume.

Traders should now look for long-biased trades in GEVA as long as it's trending above its 50-day at $68.27 or above $67 and then once it sustains a move or close above Wednesday's intraday high of $71.82 with volume that hits near or above 267,011 shares. If that move develops soon, then GEVA will set up to re-test or possibly take out its next major overhead resistance levels at $79.33 to its 200-day moving average of $81.93.

Coupons.com

Coupons.com (COUP) provides digital coupons in the U.S. This stock closed up 6.5% at $13.56 in Wednesday's trading session.

Wednesday's Volume: 793,000
Three-Month Average Volume: 511,457
Volume % Change: 75%

From a technical perspective, COUP ripped higher here right above some near-term support at $12.02 with above-average volume. This stock has been carving out a bottom over the last two months in change, with shares finding buying interest at $11.61, $11.67 and $12.02. This stock has now started to bounce higher off those support levels and it's quickly moving within range of triggering a major breakout trade. That trade will hit if COUP manages to take out its 50-day moving average of $13.71 to some more near-term overhead resistance levels at $13.81 to $14 with high volume.

Traders should now look for long-biased trades in COUP as long as it's trending above those major bottoming levels and then once it sustains a move or close above those breakout levels with volume that's near or above 511,457 shares. If that breakout gets underway soon, then COUP will set up to re-test or possibly take out its next major overhead resistance levels at $16.50 to $19.

To see more stocks rising on unusual volume, check out the Stocks Rising on Unusual Volume portfolio on Stockpickr.

-- Written by Roberto Pedone in Delafield, Wis.

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At the time of publication, author had no positions in stocks mentioned. Roberto Pedone, based out of Delafield, Wis., is an independent trader who focuses on technical analysis for small- and large-cap stocks, options, futures, commodities and currencies. Roberto studied international business at the Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany. His work has appeared on financial outlets including CNBC.com and Forbes.com. You can follow Pedone on Twitter at www.twitter.com/zerosum24 or @zerosum24.