Amazon, the world's largest online retailer, plunged 9.7% to $324.01 after reporting a net loss of 27 cents a share, far wider than an expected 15 cents a share loss, and guiding for a third-quarter operating loss as deep as $810 million.
Visa shares pulled the Dow Jones Industrial Average lower after downwardly-revising its annual revenue growth to 9% to 10% from a previous forecast of 10% to 11%. Shares closed 3.6% lower to $214.77.
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International markets also weighed on investor sentiment. The UK FTSE 100 closed 0.44% lower and the DAX in Germany was down 1.53% after the German Ifo business climate index dropped to a nine-month low of 108 amid escalating geopolitical tensions.
The S&P 500 ended the session down 0.48% to 1,978.34, after booking its 72nd closing all-time high for this bull market Thursday as analysts hiked their growth outlook for the second-quarter earnings season. The Dow was lower by 0.72% to 16,960.57 The Nasdaq slipped 0.5% to 4,449.56.
The S&P 500 is looking to end the session little changed from the beginning of the week as investors await next week's July jobs report and Federal Reserve policy update.