Watch AstraZeneca, Pfizer, Sarepta and Hasbro Today: StockTwits

NEW YORK (TheStreet) -- It's going to be a big day in the markets, especially for these top-trending companies on StockTwits.

1. Sarepta Therapeutics (SRPT) shares are surging nearly 60% this morning amid news of plans to submit an application for a new drug.

Sarepta $SRPT Plans to Submit NDA for Eteplirsen by End of 2014 http://stks.co/t0EAX

-- StreetInsider (@Street_Insider) Apr. 21 at 05:05 AM

2. Word on the street is that AstraZeneca (AZN) is in play and Pfizer (PFE) has extended a buyout offer in the neighborhood of $100 million. Shares of AZN are up over 5% in premarket as players digest the industry ramifications:

$PFE has put forward a bid of $100 billion for $AZN, according to a report published by London-based Sunday Times http://stks.co/s0EBL

-- Bidness Etc (@BidnessEtc) Apr. 21 at 07:10 AM

3. Several stocks are out with earnings this morning, and early trading action might be volatile: Hasbro  (HAS), Kimberley Clark  (KMB), Lennox International  (LII), Bank of Hawaii  (BOH), Chemical Financial (CHFC), Tennant (TNC), NVR (NVR), Washington Trust Bancorp  (WASH) and Synalloy (SYNL).

$HAS kicks things off with an EPS beat

-- Derald Muniz (@1nvestor) Apr. 21 at 04:42 AM

Kimberly-Clark $KMB Q1 Adj. EPS USD 1.41 vs. Exp. USD 1.47

-- FinancialJuice (@FinancialJuice) Apr. 21 at 05:30 AM

Halliburton $HAL beats eps by a penny. Revenues by $600m. Not a blow out like $BHI. Could see a fade like $SLB.

-- Elam Rajaguru (@bigelam) Apr. 21 at 05:35 AM

Follow me on StockTwits: @chicagosean

At the time of publication, the author held no positions in any of the stocks mentioned.

This article represents the opinion of a contributor and not necessarily that of TheStreet or its editorial staff.

More from Opinion

Sears CEO Eddie Lampert Looks Like He Is Sucking Company Dry

Sears CEO Eddie Lampert Looks Like He Is Sucking Company Dry

Nasdaq Exec: Exchange Is 'All-In' on Using Blockchain Technology

Nasdaq Exec: Exchange Is 'All-In' on Using Blockchain Technology

It's Dumb to Think Legalizing Weed Is Still a Political Issue

It's Dumb to Think Legalizing Weed Is Still a Political Issue

AAP Exclusive: Cramer Says The President is No Longer on the Side of the Bulls

AAP Exclusive: Cramer Says The President is No Longer on the Side of the Bulls

Why It Makes Perfect Sense for Netflix and Amazon to Buy Up Movie Theaters

Why It Makes Perfect Sense for Netflix and Amazon to Buy Up Movie Theaters