Alimera SciencesAlimera Sciences ( ALIM) is a biopharmaceutical company engaged in the research, development, and commercialization of ophthalmic pharmaceuticals. This stock closed up 0.89% to $2.26 in Thursday's trading session. Thursday's Range: $2.14-$2.30 52-Week Range: $1.37-$5.69 Thursday's Volume: 56,000 Three-Month Average Volume: 121,603 From a technical perspective, ALIM spiked modestly higher here with lighter-than-average volume. This stock has been trending sideways and consolidating for the last few weeks, with shares moving between $2 on the downside and $2.83 on the upside. Shares of ALIM are now starting to move within range of triggering a big breakout trade above the upper-end of its recent sideways trading chart pattern. That trade will hit if ALIM manages to take out its 50-day moving average at $2.40, and then once it clears more near-term overhead resistance levels at $2.48 to $2.83 with high volume. Traders should now look for long-biased trades in ALIM as long as it's trending above some near-term support at $2 and then once it sustains a move or close above those breakout levels with volume that hits near or above 121,603 shares. If that breakout hits soon, then ALIM will set up to re-test or possibly take out its next major overhead resistance levels at $3.50 to $4. DendreonDendreon ( DNDN) is a biotechnology company focused on the discovery, development and commercialization of novel therapeutics that improve cancer treatment options for patients. This stock closed up 4.5% to $3.21 in Thursday's trading session. Thursday's Range: $3.02-$3.23 52-Week Range: $2.23-$7.22 Thursday's Volume: 5.85 million Three-Month Average Volume: 4.26 million From a technical perspective, DNDN spiked sharply higher here and broke out above some near-term overhead resistance at $3.15 with strong upside volume. This stock has been uptrending for the last month and change, with shares moving higher from its low of $2.35 to its intraday high of $3.23. During that uptrend, shares of DNDN have been consistently making higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of DNDN within range of triggering another big breakout trade. That trade will hit if DNDN manages to take out Thursday's high of $3.23 and then once it clears more past resistance at $3.41 with high volume.