>>5 Big Trades to Take in December Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade. Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success. >>5 Stocks Insiders Love Right Now With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside today.Supernus PharmaceuticalsSupernus Pharmaceuticals ( SUPN) is a specialty pharmaceutical company focused on developing and commercializing products for the treatment of central nervous system, or CNS, diseases. This stock closed up 1.8% to $7.27 in Thursday's trading session. Thursday's Range: $6.92-$7.31 52-Week Range: $4.45-$8.40 Thursday's Volume: 510,000 Three-Month Average Volume: 531,994 From a technical perspective, SUPN spiked modestly higher here right off its 50-day moving average of $6.94 with decent upside volume. This move is quickly pushing shares of SUPN within range of triggering a big breakout trade. That trade will hit if SUPN manages to take out some near-term overhead resistance levels at $7.40 to $7.49, and then once it clears more resistance at $7.70 with high volume. Traders should now look for long-biased trades in SUPN as long as it's trending above its 50-day at $6.94 or above more near-term support at $6.77 and then once it sustains a move or close above those breakout levels with volume that hits near or above 531,994 shares. If that breakout hits soon, then SUPN will set up to re-test or possibly take out its 52-week high at $8.40.