DELAFIELD, Wis. ( Stockpickr) -- Trading stocks that trigger major breakouts can lead to massive profits. Once a stock trends to a new high, or takes out a prior overhead resistance point, then it's free to find new buyers and momentum players that can ultimately push the stock significantly higher.>>5 Short-Squeeze Stocks Ready to Pop One example of a successful breakout trade I flagged recently was air pollution control technology player Fuel Tech ( FTEK), which I featured in Nov. 7's " 5 Stocks Under $10 Set to Soar" at $4.50 share. I mentioned in that piece that shares of FTEK were consolidating in a tight chart pattern for a month, with shares moving between $4.19 on the downside and $4.78 on the upside. This stock was just starting to trend higher and move within range of triggering a big breakout trade above some near-term overhead resistance levels at $4.66 to $4.68 a share, and then above $4.78 to $5.20 a share. Guess what happened? Shares of FTEK triggered that breakout on November 12 with monster upside volume. This stock has continued to uptrend strong since entering breakout territory, with FTEK tagging a new 52-week high at $7.76 a share on last Friday. That represents a monster gain of 70% from when I wrote the original article. You can see here what a stock is capable of when it breaks out with strong upside volume flows. >>5 Stocks With Big Insider Buying Breakout candidates are something that I tweet about on a daily basis. I frequently tweet out high-probability setups, breakout plays and stocks that are acting technically bullish. These are the stocks that often go on to make monster moves to the upside. What's great about breakout trading is that you focus on trend, price and volume. You don't have to concern yourself with anything else. The charts do all the talking. Trading breakouts is not a new game on Wall Street. This strategy has been mastered by legendary traders such as William O'Neal, Stan Weinstein and Nicolas Darvas. These pros know that once a stock starts to break out above past resistance levels, and hold above those breakout prices, then it can easily trend significantly higher. >>5 Breakout Trades for the Final Stretch of 2013 With that in mind, here's a look at five stocks that are setting up to break out and trade higher from current levels.