France's Korian fell about 4% on news of its 1.1 billion euros ($1.5 billion) purchase of care-homes peer Medica, while shares in the junior merger partner rose a similar amount.
Tech giants, Big Pharma and insurers are all angling to profit from the $3 trillion-plus U.S. healthcare market.
The Danish pharmaceuticals maker is facing tighter margins and tougher competition in the U.S.
Gainers include ArcelorMittal, Lafargeholcim, Nokia, Maersk
UnitedHealth becomes the second major healthcare provider to scratch the insulin product from its 2017 medicines roster.