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(Updates from 10:45 a.m. ET with closing information and corrects the ticker symbol for Avon Products.)
NEW YORK (TheStreet) -- Here's what Jim Cramer had to say on CNBC's "Squawk on the Street" Friday.
Bernstein downgraded Vertex Pharmaceuticals (VRTX) to hold from buy. "Be careful with all the big biotech," Cramer advised, and suggested taking some profits in Gilead Sciences (GILD). VRTX fell 5.6% to $67.36.
Piper Jaffray downgraded Chart Industries (GTLS) to hold from buy. Cramer said that although he likes CEO Sam Thomas, the "shortfall is meaningful," especially after the company missed on top- and bottom-line earnings estimates. GTLS dropped 6.3% to $100.73.
Yelp (YELP) is trading well despite pricing its secondary at $67. Cramer said the "quarter was good" and investors should not "believe the critics." YELP fell 1% to $67.15.
BMO downgraded Avon Products (AVD) to hold from buy. "Avon is a disaster," Cramer stated, and CEO Sheri McCoy "has to pull it out of a tailspin and quickly." AVP rose 4.4% to $18.27.
Quintiles (Q) announced the departure of a major executive and now "people suddenly hate it," Cramer said. He agreed with the upgrade to buy from hold at Robert Baird. Q was 3.4% higher to $43.43.
Groupon (GRPN) is "making a major comeback," according to Cramer, who would bet with management rather than against them. GRPN jumped 8.7% to $9.93.