Radian Group

Radian Group ( RDN) provides credit-related insurance coverage and financial services to mortgage lenders and other financial institutions. This stock closed up 7.6% to $14.46 in Wednesday's trading session.

Wednesday's Volume: 9.35 million
Three-Month Average Volume: 4.67 million
Volume % Change: 325%

From a technical perspective, RDN ripped higher here right off its 50-day moving average of $13.58 with monster upside volume. This move pushed shares of RDN into breakout territory, since the stock took out some near-term overhead resistance levels at $14.27 to $14.42. Shares of RDN are now quickly moving within range of triggering an even bigger breakout trade. That trade will hit if RDN manages to take out Wednesday's high of $14.51 to its 52-week high at $14.80 with high volume.

Traders should now look for long-biased trades in RDN as long as it's trending above its 50-day at $13.58 and then once it sustains a move or close above those breakout levels with volume that hits near or above 4.67 million shares. If that breakout hits soon, then RDN will set up to enter new 52-week-high territory, which is bullish technical price action. Some possible upside targets off that move are $17 to $20.

Portola Pharmaceuticals

Portola Pharmaceuticals ( PTLA) is a biopharmaceutical company that develops and commercializes novel therapeutics in the areas of thrombosis, other hematologic disorders and inflammation for patients who currently have limited or no approved treatment options. This stock closed up 11.9% to $25.55 in Wednesday's trading session.

Wednesday's Volume: 1.03 million
Three-Month Average Volume: 78,362
Volume % Change: 1075%

From a technical perspective, PTLA exploded higher here back above its 50-day moving average of $24.22 with monster upside volume. This move is quickly pushing shares of PTLA within range of triggering a major breakout trade. That trade will hit if PTLA manages to take out Wednesday's high of $26.70, and then once it clears its all-time high of $30.95 with high volume.

Traders should now look for long-biased trades in PTLA as long as it's trending above its 50-day at $24.22 or above $23 and then once it sustains a move or close above those breakout levels with volume that hits near or above 78,362 million shares. If that breakout hits soon, then PTLA will set up to enter new all-time-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $35 to $40.

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