Astex Pharmaceuticals To Present At AACR-NCI-EORTC

DUBLIN, Calif., Oct. 14, 2013 (GLOBE NEWSWIRE) -- Astex Pharmaceuticals, Inc., a pharmaceutical company dedicated to the discovery and development of novel small molecule therapeutics, today announced four presentations of developmental and collaboration programs will be made at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Oct. 20 and 21, in Boston.
SGI-110 Abstract # A256  
Poster Presentation  Sunday, Oct. 20 12:30 - 7:30 p.m. EDT
Improved Antitumor Activity by Sequencing SGI-110 with CTLA-4 Blockade in a Syngenic Mouse Model
     
XIAP Abstract #A55  
Poster Presentation  Sunday, Oct. 20 12:30 - 7:30 p.m. EDT
Potent, dual cIAP1/XIAP antagonists induce apoptosis in a melanoma stem cell population
     
LEE011 Abstract #PR02  
Proffered Paper Session Sunday, Oct. 20 5:45 – 6 p.m. EDT
     
  Abstract #B264  
Novartis Poster Presentation Monday, Oct. 21 12:30 – 3 p.m. & 6:30 – 7:30 p.m. EDT
LEE011- An orally bioavailable, selective small molecule inhibitor of CDK4/6: Reactivating Rb in cancer
     
LEE011 Abstract #A276  
Novartis Poster Presentation Sunday, Oct. 20 12:30 - 3 p.m. & 6:30 – 7:30 p.m. EDT
Phase 1 multicenter, open label, dose-escalation study of LEE011, an oral inhibitor of cyclin-dependent kinase 4/6, in patients with advanced solid tumors or lymphomas

Select posters will be made available for viewing on the Astex website http://astx.com/pipeline/publications/.

About Astex Pharmaceuticals

Astex Pharmaceuticals is dedicated to the discovery and development of novel small molecule therapeutics with a focus on oncology. Astex is developing a proprietary pipeline of novel therapies and is creating de-risked products for collaborations with leading pharmaceutical companies. Astex Pharmaceuticals developed DACOGEN® (decitabine) for Injection and receives significant royalties on global sales.

For more information about Astex Pharmaceuticals, Inc., please visit http://www.astx.com.

CONTACT: Timothy L. Enns         Astex Pharmaceuticals, Inc.         Senior Vice President         Corporate Communications & Marketing         Tel:  +1 (925) 560-2810         E-mail:  tim.enns@astx.com                  Susanna Chau         Astex Pharmaceuticals, Inc.         Manager         Tel:  +1 (925) 560-2845         E-mail:  susanna.chau@astx.com

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