Exploratory efficacy analyses suggested that efficacy was approximately equal in patients with greater than 10 percent body surface area involvement and in patients with 5 to 10 percent body surface area involvement prior to treatment.The compound was generally well-tolerated with no evidence of myelosuppression. Decreases in platelet counts were observed, but the counts generally remained within normal limits. Increases in LDL and HDL were also noted without a significant change in the HDL/LDL ratio. To access the presentation: INCB39110 EADV Presentation “Our proof-of-concept studies of INCB39110 in psoriasis, rheumatoid arthritis and myelofibrosis are providing us with greater insight and confirm our belief that JAK1 inhibition may be of benefit in chronic inflammatory disorders as well as oncologic indications,” stated Richard S. Levy, Incyte’s Executive Vice President and Chief Drug Development and Medical Officer. “With our portfolio of JAK1 inhibitors, we’re well-positioned to potentially pursue development in chronic inflammatory conditions and oncology with separate molecules, as we did with our JAK1/JAK2 inhibitor program.” About INCB39110 INCB39110 is the most advanced compound within Incyte’s portfolio of selective JAK1 inhibitors and is being evaluated in Phase II proof-of-concept trials in psoriasis, rheumatoid arthritis and myelofibrosis and an initial Phase I/II safety study in combination with gemcitabine and nab-paclitaxel in patients with advanced solid tumors to help define its clinical efficacy and safety profile, understand potential points of differentiation between JAK1 and JAK1/JAK2 inhibition and determine the most appropriate path forward for further development. About Incyte Incyte Corporation is a Wilmington, Delaware-based biopharmaceutical company focused on the discovery, development and commercialization of proprietary small molecule drugs for oncology and inflammation. For additional information on Incyte, please visit the Company's website at www.incyte.com. Forward-Looking Statements Except for the historical information set forth herein, the matters set forth in this press release, including without limitation statements with respect to the potential efficacy and safety and therapeutic potential of INCB39110, our belief that JAK1 inhibition may be of benefit in chronic inflammatory disorders as well as oncologic indications, and our potential to pursue development in chronic inflammatory conditions and oncology with separate JAK1 inhibitor molecules, contain predictions and estimates and are forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are based on Incyte’s current expectations and subject to risks and uncertainties that may cause actual results to differ materially, including unanticipated developments in and risks related to the efficacy or safety of INCB39110, the results of further research and development, other market, economic or strategic factors and technological advances, and other risks detailed from time to time in Incyte's filings with the Securities and Exchange Commission, including its Quarterly Report on Form 10-Q for the quarter ended June 30, 2013. Incyte disclaims any intent or obligation to update these forward-looking statements.