NEW YORK ( TheStreet) -- Large regional banks were losers on Thursday, on the prospect of relatively weak third-quarter results. The KBW Bank Index ( I:BKX) was down 0.3% to close at 62.53, with 14 of the 24 index components ending with declines. Large regional banks with shares pulling back 1% included Comerica ( CMA) of Dallas, which closed at $39.27; Huntington Bancshares ( HBAN) of Columbus, Ohio, at $8.27; KeyCorp ( KEY) of Cleveland, at $11.34; PNC Financial Services Group of Pittsburgh ( PNC), at $72.44; and Regions Financial ( RF) of Birmingham, Ala., which closed at $9.18. In his firm's third-quarter earnings preview for U.S. Regional banks, Credit Suisse analyst Nick Karzon late on Wednesday wrote that "lower mortgage banking revenues are still not fully embedded in consensus EPS estimates," for many banks. Third-quarter mortgage revenue is expected to drop in the double digits for many large banks, as refinance applications have slowed considerably on rising long-term interest rates. Gain-on-sale margins for new residential loans sold to Fannie Mae ( FNMA) and Freddie Mac ( FMCC) will also be sharply lower, because of the rise in long-term rates. Karzon didn't change his third-quarter estimates for the regional banks covered by Credit Suisse, however, he estimated that BB&T ( BBT) of Winston-Salem, N.C., would see its third-quarter mortgage loan origination volume decline to $7.0 billion from $9.3 billion during the second quarter. For Regions Financial, the analyst estimated origination volume would see a sequential decline to $1.5 billion from $1.9 billion, while for SunTrust ( STI) of Atlanta, Karzon estimated a decline in mortgage loan origination volume to $7.4 billion in the third quarter from $9.1 billion in the second quarter.