52-Week Range: $0.73-$3.97 Tuesday's Volume: 920,000 Three-Month Average Volume: 194,859 From a technical perspective, PTIX skyrocketed higher here and broke out above some near-term overhead resistance levels at $3.20 to $3.43 with high volume. This stock has been trending sideways for the last month, with shares moving between $2.59 on the downside and $3.43 on the upside. This move has started to push shares of PTIX within range of triggering a big breakout trade. That trade will hit if PTIX manages to take out Tuesday's intraday high of $3.44 and then once it clears its 52-week high at $3.97 with high volume. Traders should now look for long-biased trades in PTIX as long as it's trending above $3.20 or $3, and then once it sustains a move or close above those breakout levels with volume that's near or above 194,859 shares. If that breakout hits soon, then PTIX will set up to enter new 52-week high territory, which is bullish technical price action. Some possible upside targets off that breakout are $5 to $6. GTX ( GTXI) This is a biopharmaceutical company dedicated to the discovery, development and commercialization of small molecules that selectively target hormone pathways to treat cancer, osteoporosis and bone loss, muscle loss and other serious medical condition. This stock closed up 5.3% to $1.59 in Tuesday's trading session. Tuesday's Range: $1.53-$1.63 52-Week Range: $1.31-$7.24 Tuesday's Volume: 1.50 million Three-Month Average Volume: 1.25 million From a technical perspective, GTXI ripped sharply higher here right off some near-term support at $1.50 with strong upside volume. This move is quickly pushing shares of GTXI within range of triggering a major breakout trade. That trade will hit if GTXI manages to take out some near-term overhead resistance at Tuesday's intraday high of $1.63 to more resistance at $1.67 with high volume. Traders should now look for long-biased trades in GTXI as long as it's trending above support at $1.50 or above its recent low of $1.31, and then once it sustains a move or close above those breakout levels with volume that hits near or above 1.25 million shares. If that breakout hits soon, then GTXI will set up to re-fill some of its previous gap down zone from August that started just above $4. Some possible upside targets for GTXI if it gets into that gap with volume are $2 to $2.50.