"In this study the HLT Patch administered once or twice daily for pain of lateral epicondylitis resulted in the majority of patients experiencing clinically meaningful reductions in pain comparable to that seen with oral naproxen. The HLT Patch may offer a novel significant clinical option by providing a locally targeted treatment which minimizes the risks of systemic adverse effects for patients with tennis elbow pain," said Srinivas Nalamachu, MD, principal investigator, International Clinical Research Institute Inc., Overland Park, KS.Study 2 The study in the second poster compared the efficacy of the HLT Patch vs a single corticosteroid injection for the treatment of shoulder impingement syndrome (SIS) pain in a 6-week, randomized, open-label study which enrolled 60 adult subjects. Both groups demonstrated a significant (P<.001) reduction in average pain scores at 2 weeks compared with baseline (-35%±29% and -42%±36% in the HLT Patch and injection groups, respectively), which were sustained through 6 weeks (-43%±34% and -43%±41%, respectively). Significant improvements in shoulder range of motion were also seen in both treatment groups by treatment week 2 and sustained throughout the entire 6 week study. Mild to moderate application site erythema was the most common treatment related adverse event observed in 22 of 29 HLT Patch patients. "In this study, the HLT Patch provided similar degrees of improvement in both pain and range of motion, when compared to the current gold-standard treatment of steroid injection. Being able to treat shoulder impingement effectively, while avoiding the potential problems of steroids and injections, is a significant clinical advantage," said Richard Radnovich, D.O., principle investigator, Injury Care Medical Center, Boise, Idaho. Study 3 The third poster will be presenting a pooled analysis that examined the relationship between decreased pain scores and improved function in 73 subjects treated with HLT Patch in four open-label pilot studies for AMP associated with SIS, patellar tendinopathy, carpal tunnel syndrome and myofascial trigger points. Approximately one third of patients treated with the HLT Patch achieved a ≥50% reduction in average pain scores, which was also associated with 1.5- to 2-fold greater functional improvement.