Agilent Technologies Inc. (NYSE: A) today announced the launch of its new AssayMAP peptide sample-prep solution, which offers automated protein digestion, peptide cleanup and fractionation in preparation for mass-spectrometry analysis.
The Agilent AssayMAP peptide sample-prep solution offers automated protein digestion, peptide cleanup and fractionation in preparation for mass-spectrometry analysis. (Photo: Business Wire)As more scientists adopt LC/MS analysis for biomarker discovery, the bottleneck shifts to sample preparation. As these types of studies involve much larger numbers of samples, traditional manual methods are proving untenable in terms of hands-on time and unreliable in terms of reproducibility. “Using the combination of extremely consistent, parallelized digestion with automated reverse-phase cleanup via AssayMAP, at a scale appropriate for ultrasensitive proteomics applications, has enabled us to contemplate collaborative studies of previously unheard-of scales and throughput,” said Jacob Jaffe, Ph.D., assistant director of proteomics platforms at the Broad Institute in Cambridge, Mass. “The AssayMAP peptide sample-preparation solution is one of the ways Agilent is addressing the need for high-throughput, reproducible sample-preparation methods in front of precision analytical instruments,” said Kathleen Shelton, senior director of automation marketing at Agilent. “Agilent’s unique ability to deliver high-quality solutions for automating sample preparation through analysis enables scientists to maximize workflow productivity and be more successful.” AssayMAP helps address the bottleneck created with traditional sample preparation for mass-spec analysis and enables unprecedented precision and throughput. This easy-to-use solution includes validated automation protocols driven through intuitive software, the AssayMAP Bravo liquid-handling instrument, and a suite of AssayMAP cartridges optimized for peptide cleanup and fractionation. The AssayMAP peptide sample-prep solution makes large campaigns possible for mass-spec analysis, leveraging the strength of this analytical method to unambiguously identify peptides.