Study 171Study 171 was an open-label study involving 518 patients with type 1 diabetes on basal/bolus insulin therapy who were studied at sites in the United States, Russia, Ukraine and Brazil. After a four-week run-in period to optimize their basal insulin, patients entered a 24-week treatment period in which they were randomized in one of three ways:
- Continuing on subcutaneous insulin aspart in combination with a basal insulin (170 patients);
- Switching to AFREZZA administered using the Gen2 inhaler in combination with their basal insulin (174 patients); or
- Switching to AFREZZA administered using the MedTone inhaler in combination with their basal insulin (174 patients).