2. As of noon trading, Shire ( SHPG) is up $5.55 (5.4%) to $108.07 on heavy volume. Thus far, 712,897 shares of Shire exchanged hands as compared to its average daily volume of 547,000 shares. The stock has ranged in price between $105.37-$109.06 after having opened the day at $105.80 as compared to the previous trading day's close of $102.52. Shire plc, a specialty biopharmaceutical company, engages in the research and development, manufacture, sale, and distribution of pharmaceutical products. It operates in three segments: Specialty Pharmaceuticals (SP), Human Genetic Therapies (HGT), and Regenerative Medicine (RM). Shire has a market cap of $18.9 billion and is part of the drugs industry. Shares are up 11.2% year to date as of the close of trading on Wednesday. Currently there are 9 analysts that rate Shire a buy, no analysts rate it a sell, and 4 rate it a hold. TheStreet Ratings rates Shire as a buy. The company's strengths can be seen in multiple areas, such as its largely solid financial position with reasonable debt levels by most measures, expanding profit margins and increase in stock price during the past year. We feel these strengths outweigh the fact that the company has had sub par growth in net income. Get the full Shire Ratings Report now. 3x UPSIDE POTENTIAL: TheStreet Quant Ratings has identified a handful of stocks that can potentially TRIPLE in the next 12-months. Learn more.