DELAFIELD, Wis. ( Stockpickr) -- Professional traders running mutual funds and hedge funds don't just look at a stock's price moves; they also track big changes in volume activity. Often when above-average volume moves into an equity, it precedes a large spike in volatility.>>5 Stocks Poised for Big Breakouts Major moves in volume can signal unusual activity, such as insider buying or selling -- or buying or selling by "superinvestors." Unusual volume can also be a major signal that hedge funds and momentum traders are piling into a stock ahead of a catalyst. These types of traders like to get in well before a large spike, so it's always a smart move to monitor unusual volume. That said, remember to combine trend and price action with unusual volume. Put them all together to help you decipher the next big trend for any stock. >>4 Big Stocks on Traders' Radars With that in mind, let's take a look at several stocks rising on unusual volume today. Cepheid Cepheid ( CPHD) is a molecular diagnostics company that develops, manufactures and markets integrated systems for testing in the clinical market, as well as for application in its non-clinical market. This stock closed up 3.1% to $35.22 in Friday's trading session. Friday's Volume: 4.11 million
Three-Month Average Volume: 551,367
Volume % Change: 693% Shares of CPHD rose on Friday after the company's second-quarter adjusted profit surprised Wall Street and revenue beat analysts' estimates. >>5 Must-See Charts to Buy in July From a technical perspective, CPHD ripped higher here back above its 200-day moving average at $35.10 with heavy upside volume. This move is quickly pushing CPHD within range of triggering a near-term breakout trade. That trade will hit if CPHD manages to take out Friday's high of $35.67 and then once it clears some more resistance at $36.49 with high volume. Traders should now look for long-biased trades in CPHD as long as it's trending above $34 and then once it sustains a move or close above those breakout levels with volume that hits near or above 551,367 shares. If that breakout triggers soon, then CPHD will set up to re-test or possibly take out its next major overhead resistance levels at $39.15 to $40.31.