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(Updates from 10:35 a.m. ET with closing information.) NEW YORK ( TheStreet) -- Here's what Jim Cramer had to say on CNBC's "Squawk On The Street" Wednesday. Biogen Idec ( BIIB) investors are worried about drug protection in Europe but Cramer thinks it's overdone and Biogen is fine. BIIB ended Wednesday down 7.4% to $206.55. Manitowoc ( MTW) should be split into two companies, according to Cramer. Ice machines and cranes "don't fall under the same roof," he said. MTW was 2.2% lower at $18.59. Citigroup upgraded Applied Materials ( AMAT) to buy from neutral. Cramer agreed with the call. AMAT was flat at $15.25. Google ( GOOG) has a new $1,000 price target. Cramer loves the company and raised his target to $1,001, saying Google is "very solid." GOOG fell nearly 1% to $871.98. Royal Bank of Scotland ( RBS) is one of Cramer's favorite speculation plays, he said. "I think it goes much higher." RBS closed at $9.84, down 3.8%. Tesla Motors' ( TSLA) price target was raised by Baird, but Cramer thinks the stock has run too far, too fast. He said Tesla is "a sell." TSLA was up 3.5% to $97.73. To sign up for Jim Cramer's free Booyah! newsletter, with all of his latest articles and videos, please click here. -- Written by Bret Kenwell in Petoskey, Mich. Follow @traderboy23