Tuesday's Volume: 1.37 million Average Volume: 556,850 Volume % Change: 148% >>5 Stocks Under $10 Set to Soar Shares of VPHM were on the move Tuesday after the company said subgroup analyses of its pivotal and open label prevention trials showed effectiveness of its Cinryze in prevention of angioedema attacks in patients with hereditary angioedema poorly controlled on anabolic androgens. From a technical perspective, VPHM trended higher here and broke out above some near-term overhead resistance levels at $27.40 to $27.46 with above-average volume. Those levels have acted as tough resistance for VPHM for over the last five months, so this breakout could be setting up VPHM for a sharp move higher. Traders should now look for long-biased trades in VPHM as long as it's trending above $27 and then once it sustains a move or close above Tuesday's high of $28.19 with volume that hits near or above 556,850 shares. If we get that move soon, then VPHM will set up to re-test or possibly take out its next major overhead resistance levels at $30 to $31.36. Any high-volume move above $31.36 will then put $33 into range for shares of VPHM. Puma BiotechnologyPuma Biotechnology ( PBYI) is a development-stage biopharmaceutical company that acquires and develops innovative products for the treatment of various forms of cancer. This stock closed up 2.4% at $39.33 on Tuesday. Tuesday's Volume: 483,000 Average Volume: 145,031 Volume % Change: 249% From a technical perspective, PBYI spiked notably higher here with above-average volume. This stock has been uptrending strong for the last month, with shares soaring higher from its low of $27.40 to its recent high of $39.72. During that move, shares of PBYI have been mostly making higher lows and higher highs, which is bullish technical price action. That move is quickly pushing shares of PBYI within range of triggering a near-term breakout trade. That trade will hit if PBYI can manage to clear its all-time high at $39.72 with high volume. Traders should now look for long-biased trades in PBYI as long as it's trending above $38 or $37 and then once it sustains a move or close above $39.72 with volume that hits near or above 145,031 shares. If we get that breakout, then PBYI will set up to enter new all-time-high territory, which is bullish technical price action. Some possible upside targets off that breakout are $43 to $45.