PacBio ® RS II With BluePippin™ Size Selection Platform Provides Customers Improved Ability to Sequence Longer DNA Fragments MENLO PARK, Calif. and BEVERLY, Mass., May 16, 2013 (GLOBE NEWSWIRE) -- Pacific Biosciences of California, Inc., (Nasdaq:PACB), provider of the PacBio ® RS II DNA Sequencing System, and Sage Science, a developer of life science products for improving sample preparation processes in molecular biology applications, today announced a co-marketing partnership to provide customers of the PacBio RS II the ability to sequence even longer DNA fragments when performing Single Molecule, Real-Time (SMRT ®) Sequencing. "We have found that the BluePippin™ size selection platform is very useful for applications where long read lengths are important, such as de novo genome assembly," said Kevin Corcoran, Senior Vice President of Market Development at Pacific Biosciences. "Our studies have demonstrated that size selection with Sage's BluePippin platform is an easy addition to our customers' sample prep workflow that selects for 10 kb or larger fragments for sequencing on the PacBio RS II." Based on PacBio's revolutionary SMRT Sequencing technology, the PacBio RS II can generate average read lengths of 5,000 base pairs, with the longest reads above 20,000 base pairs in length. The PacBio RS II System, including consumables and software, provides a simple, fast, end-to-end workflow for SMRT Sequencing in research areas including infectious disease and microbiology, agriculture, and complex genetic diseases with repeat expansions. The BluePippin platform, part of the Pippin line of automated size-selection tools offered by Sage Science, uses pulsed-field power to take fractions of DNA from fragments ranging from 50 bases to 50 kilobases. Independent studies of size-selection methods for next-generation sequencing sample prep have repeatedly found that the Pippin platform offers unparalleled reproducibility, accuracy, and sample recovery. By eliminating low-molecular-weight templates from sequencing libraries, automated size selection allows users to load longer fragments and boost the average read length produced by sequencing.