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Editor's Note: TheStreet ratings do not represent the views of TheStreet's staff or its contributors. Ratings are established by computer based on metrics for performance (which includes growth, stock performance, efficiency and valuation) and risk (volatility and solvency). Companies with poor cash flow or high debt levels tend to earn lower ratings in our model. NEW YORK ( TheStreet) -- Isis Pharmaceuticals (Nasdaq: ISIS) hit a new 52-week high Friday as it is currently trading at $22.95, above its previous 52-week high of $22.90 with 125,437 shares traded as of 10:05 a.m. ET. Average volume has been 1.4 million shares over the past 30 days. Isis has a market cap of $2.22 billion and is part of the health care sector and drugs industry. Shares are up 106% year to date as of the close of trading on Thursday. Isis Pharmaceuticals, Inc. engages in the discovery and development of antisense drugs using novel drug discovery platform.