A health care stock that insiders are snapping up shares in here is Express Scripts ( ESRX), which offers health care management and administration services such as managed care organizations, health insurers, workers' compensation plans and government health programs. Insiders are buying this stock into decent strength, since shares are up 10% so far in 2013. Express Scripts has a market cap of $48 billion and an enterprise value of $62 billion. This stock trades at a reasonable valuation, with a trailing price-to-earnings of 33.92 and a forward price-to-earnings of 12.09. Its estimated growth rate for this year is 14.2%, and for next year it's pegged at 15.2%. This is not a cash-rich company, since the total cash position on its balance sheet is $2.79 billion and its total debt is a whopping $15.92 billion. A director just bought 5,000 shares, or about $297,000 worth of stock, at $59.58 per share. From a technical perspective, ESRX is currently trending above both its 50-day and 200-day moving averages, which is bullish. This stock has been uptrending strong for the last five months, with shares soaring higher from its low of $49.79 to its recent high of $60.08 a share. During that uptrend, shares of ESRX have been consistently making higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of ESRX within range of triggering a major breakout trade. If you're bullish on ESRX, then look for long-biased trades as long as this stock is trending above its 200-day at $57.28 or its 50-day at $56.06 and then once it breaks out above some near-term overhead resistance at $60.08 a share with high volume. Look for a sustained move or close above $60.08 a share with volume that registers near or above its three-month average action of 5.96 million shares. If that breakout triggers soon, then ESRX will set up to re-fill some of its previous gap down zone from last November that started at $63 a share. Any high-volume move above $63 will then put $65 to $66 into range for shares of ESRX.