AffymaxAffymax ( AFFY) is a biopharmaceutical company committed to developing novel drugs to improve the treatment of serious and often life-threatening conditions. This stock closed up 5.1% to $3.06 on Thursday. Thursday's Range: $2.90-$3.39 52-Week Range: $2.26-$27.74 Volume: 14.99 million Three-Month Average Volume: 4.34 million From a technical perspective, AFFY bounced higher here right above some near-term support at $2.86 with heavy upside volume. Shares of AFFY have been consolidating for the last few trading sessions, with the stock trading just above and below $3 a share. That action now has AFFY trending within range of triggering a major breakout trade. That trade will hit if AFFY manages to take out $4 to $4.10 with high volume. Traders should now look for long-biased trades in AFFY if it manages to break out above $4 to $4.10 with strong upside volume flows. Look for a sustained move or close above those breakout levels with volume that hits near or above its three-month average action of 4.34 million shares. If that breakout triggers soon, then AFFY will set up to trade into its previous gap down zone from last month that started near $16. Some possible upside targets if we get into that gap with volume are $6 to $8. Acasti PharmaAcasti Pharma ( ACST) is engaged in the research, development and commercialization of proprietary active pharmaceutical ingredients, primarily applied in the management of cardio metabolic disorders. This stock closed up 5.6% to $2.40 on Thursday. Thursday's Range: $2.25-$2.49 52-Week Range: $1.61-$3.99 Volume: 118,000 Three-Month Average Volume: 28,337 From a technical perspective, ACST bounced higher here right off its 200-day moving average at $2.23 with above-average volume. This move is quickly pushing shares of ACST within range of triggering a near-term breakout trade. That trade will hit if ACST manages to take out its 50-day moving average at $2.45 and then once it clears more overhead resistance at $2.60 to $2.66 with high volume. Traders should now look for long-biased trades in ACST as long as it's trending above its 200-day at $2.23 and then once it sustains a move or close above those breakout levels with volume that hits near or above 28,337 shares. If that breakout triggers soon, then ACST will set up to re-test or possibly take out its next major overhead resistance level $2.99. Any high-volume move above $2.99 will then put $3.99 into range for shares of ACST.