"Previous studies have shown the value of Oncotype DX in predicting chemotherapy benefit in both node-negative and node-positive breast cancer. Based on the results presented by Dr. Mamounas, we now have evidence suggesting the value of the Oncotype DX result in tailoring the intensity and extent of radiation in breast cancer patients with node-positive disease," said Steven Shak, M.D., chief medical officer and executive vice president for research and development at Genomic Health. "This study, combined with an upcoming publication in DCIS, demonstrates our continued efforts in helping physicians and breast cancer patients answer important treatment decision questions about the intensity of their radiation therapy."The parent NSABP B-28 trial was funded by the National Cancer Institute with additional support from Bristol Myers Squibb. The study evaluating the prognostic impact of the 21-gene Recurrence Score on loco-regional recurrence was funded through a grant from the Susan G. Komen for the Cure Foundation. About Genomic Health Genomic Health, Inc. (NASDAQ: GHDX) is a global healthcare company that provides actionable genomic information to personalize cancer treatment decisions. The company's lead product, the Oncotype DX® breast cancer test, has been shown to predict the likelihood of chemotherapy benefit as well as recurrence in invasive breast cancer and has been shown to predict the likelihood of recurrence in ductal carcinoma in situ (DCIS). In addition to this widely adopted test, Genomic Health provides the Oncotype DX colon cancer test, the first multi-gene expression test developed for the assessment of risk of recurrence in patients with stage II and stage III disease. As of December 31, 2012, more than 10,000 physicians in over 70 countries had ordered approximately 335,000 Oncotype DX tests. Genomic Health has a robust pipeline focused on developing tests to optimize the treatment of prostate and renal cell cancers, as well as additional treatment decisions in breast and colon cancers. The company is based in Redwood City, California with European headquarters in Geneva, Switzerland. For more information, please visit, www.GenomicHealth.com. To learn more about Oncotype DX tests, visit: www.OncotypeDX.com and www.mybreastcancertreatment.org. This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including statements relating to the ability of the company's Oncotype DX test to predict loco regional recurrence in node positive breast cancer patients and the potential ability of the test to be used in radiation treatment decisions; the applicability of clinical study results to actual outcomes; the scope, success or results of clinical trials and the timing of such activities; the ability of the test to impact clinical practice ; the expectations and timing for the publication of the DCIS validation study; the ability of the company to develop additional tests in the future; the attributes and focus of the company's product pipeline; the potential economic benefits associated with the company's tests; and the demand for the company's tests. Forward-looking statements are subject to risks and uncertainties that could cause actual results to differ materially and reported results should not be considered as an indication of future performance. These risks and uncertainties include, but are not limited to: the results of clinical studies ; the applicability of clinical study results to actual outcomes; the risks and potential delays associated with such studies ; the risks and uncertainties associated with publication of the DCIS validation study; the risks and uncertainties associated with possible additional regulation of the company's tests both in the United States and abroad;; the risks associated with competition; unanticipated costs or delays in research and development efforts; and the other risks set forth in the company's filings with the Securities and Exchange Commission, including the risks set forth in the company's Quarterly Report on Form 10-Q for the quarter ended September 30, 2012. These forward-looking statements speak only as of the date hereof. Genomic Health disclaims any obligation to update these forward-looking statements. NOTE: The Genomic Health logo, Oncotype, Oncotype DX, Recurrence Score, and DCIS Score are trademarks or registered trademarks of Genomic Health, Inc. All other trademarks and service marks are the property of their respective owners.