earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade. >>5 Stocks Ready for Breakouts Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success. With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside today. >>5 Hated Earnings Stocks Poised to Pop Trius Therapeutics Trius Therapeutics ( TSRX) is a biopharmaceutical company focused on the discovery, development and commercialization of innovative antibiotics for serious, life-threatening infections. This stock is trading up 7.3% to $5.90 in recent trading. Today's Range: $5.49-$5.93 52-Week Range: $4.41-$6.49 Volume: 772,000 Three-Month Average Volume: 482,365 From a technical perspective, TSRX is soaring higher here right above its 200-day moving average of $5.38 with heavy upside volume. This move has started to push shares of TSRX into breakout territory, since it's taken out some near-term overhead resistance at $5.69. Shares of TSRX are now quickly moving within range of triggering another major breakout trade. That trade will hit if TSRX manages to take out its next major overhead resistance levels at $5.90 to $5.93 with high volume. Traders should now look for long-biased trades in TSRX as long as it's trending above $5.69 or today's low of $5.49, and then once it sustains a move or close above those breakout levels with volume that hits near or above 482,365 shares. If that breakout triggers soon, then TSRX will set up to re-test or possibly take out its next major overhead resistance levels at $6.46 to $6.49. If those levels get taken out with volume then $7.44 to $8 will come into range for shares of TSRX.